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Anti-RANK/TNFRSF11A Antibody (5X794)

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货号 TMAY-03761

别名 tumor necrosis factor receptor superfamily member 11a, TRANCER, TNFRSF11A, RANK, PDB2, OSTS, OPTB7, OFE, ODFR, LOH18CR1, FEO, CD265

Anti-RANK/TNFRSF11A Antibody (5X794) 是一种 Rabbit 抗体,靶向 RANK/TNFRSF11A。Anti-RANK/TNFRSF11A Antibody (5X794) 可用于 ELISA。

Anti-RANK/TNFRSF11A Antibody (5X794)

Anti-RANK/TNFRSF11A Antibody (5X794)

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货号 TMAY-03761 别名 tumor necrosis factor receptor superfamily member 11a, TRANCER, TNFRSF11A, RANK, PDB2, OSTS, OPTB7, OFE, ODFR, LOH18CR1, FEO, CD265

Anti-RANK/TNFRSF11A Antibody (5X794) 是一种 Rabbit 抗体,靶向 RANK/TNFRSF11A。Anti-RANK/TNFRSF11A Antibody (5X794) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,284
5日内发货
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产品介绍


生物活性
产品描述
Anti-RANK/TNFRSF11A Antibody (5X794) is a Rabbit antibody targeting RANK/TNFRSF11A. Anti-RANK/TNFRSF11A Antibody (5X794) can be used in ELISA.
别名tumor necrosis factor receptor superfamily member 11a, TRANCER, TNFRSF11A, RANK, PDB2, OSTS, OPTB7, OFE, ODFR, LOH18CR1, FEO, CD265
Ig Type
Rabbit IgG
克隆号
5X794
反应种属
Rat
特异性
Rat RANK/TNFRSF11A
No cross-reactivity in ELISA with
Rat EDAR
应用ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Rat TNFRSF11A (TMPY-02851; XP_573424.2; Met1-Pro213).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. It is an essential mediator for osteoclast and lymph node development. TNFRSF11A and its ligand are important regulators of the interaction between T cells and dendritic cells. It can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. Defects in TNFRSF11A can cause familial expansile osteolysis (FEO). FEO is a rare autosomal dominant bone disorder characterized by focal areas of increased bone remodeling. Defects in TNFRSF11A also can cause Paget disease of bone type 2 (PDB2). PDB2 is a bone-remodeling disorder with clinical similarities to FEO. Defects in TNFRSF11A are the cause of osteopetrosis autosomal recessive type 7 which characterized by abnormally dense bone, due to defective resorption of immature bone.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Rat TNFRSF11A protein (TMPY-02851)
抗原种属
Rat
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.
存储-20°C for 1 year

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