OX40/TNFRSF4 Protein, Cynomolgus, Recombinant (His)

OX40/TNFRSF4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35-50 KDa and the accession number is XM_005545122.1.

规格	价格/CNY		数量
10 μg	￥ 1,170	5日内发货
50 μg	￥ 3,470	5日内发货
500 μg	￥ 13,200	5日内发货
1 mg	￥ 18,900	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 1,170

5日内发货

50 μg

￥ 3,470

5日内发货

500 μg

￥ 13,200

5日内发货

1 mg

￥ 18,900

5日内发货

生物活性	Loaded Biotinylated Cynomolgus OX40-His on HIS1K Biosensor, can bind Human OX40L-mFc with an affinity constant of 0.05nM as determined in BLI assay. (Regularly tested)
产品描述	OX40/TNFRSF4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35-50 KDa and the accession number is XM_005545122.1.

种属	Cynomolgus
表达系统	HEK293 Cells
标签	C-6xHis
蛋白编号	XM_005545122.1
别名	CD134, Tnfrsf4, Txgp1, OX40, Tumor necrosis factor receptor superfamily member 4
氨基酸序列	Lys28-Ala214
蛋白构建	Lys28-Ala214
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	35-50 KDa (reducing condition)

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases.

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OX40/TNFRSF4 Protein, Cynomolgus, Recombinant (His)

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