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顶部生物活性储存和溶解信息计算器

Anti-Phospho-STAT1 (Ser727) Polyclonal Antibody

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Anti-Phospho-STAT1 (Ser727) Polyclonal Antibody
产品编号 TMAC-03868
别名 STAT1 (p-Ser727), STAT1 (p-S727), p-STAT1 (Ser727), p-STAT1 (S727)

Anti-Phospho-STAT1 (Ser727) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-STAT1 (Ser727)。Anti-Phospho-STAT1 (Ser727) Polyclonal Antibody 可用于 WB,IHC,IF。

Anti-Phospho-STAT1 (Ser727) Polyclonal Antibody

Anti-Phospho-STAT1 (Ser727) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-STAT1 (Ser727) Polyclonal Antibody
产品编号 TMAC-03868 别名 STAT1 (p-Ser727), STAT1 (p-S727), p-STAT1 (Ser727), p-STAT1 (S727)

Anti-Phospho-STAT1 (Ser727) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-STAT1 (Ser727)。Anti-Phospho-STAT1 (Ser727) Polyclonal Antibody 可用于 WB,IHC,IF。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,230
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-STAT1 (Ser727) Polyclonal Antibody is a Rabbit antibody targeting Phospho-STAT1 (Ser727). Anti-Phospho-STAT1 (Ser727) Polyclonal Antibody can be used in WB,IHC,IF.
别名STAT1 (p-Ser727), STAT1 (p-S727), p-STAT1 (Ser727), p-STAT1 (S727)
Ig Type
IgG
交叉反应
Human,Mouse
验证活性
1. Western blot analysis of extracts from Hela cells using STAT1 (Phospho-Ser727) Antibody TMAC-03868.
2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT1 (Phospho-Ser727) Antibody TMAC-03868 (left) or the same antibody preincubated with blocking peptide (right).
3. Immunofluorescence staining of methanol-fixed Hela cells using STAT1 (Phospho-Ser727) Antibody TMAC-03868.
应用
WB
IHC
IF
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Signal transducer and activator of transcription that mediates signaling by interferons (IFNs). Following type I IFN (IFN-a and IFN-beta) binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of serine 727 (P-M-S(p)-P-E) derived from Human STAT1
抗原种属
human
Uniprot ID
P42224
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

STAT1 (pSer727)STAT1 (pS727)STAT1 (phospho-Ser727)STAT1 (phospho-S727)pSTAT1 (Ser727)pSTAT1 (S727)

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4个月前
5.0
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