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Anti-Lipin 3 Polyclonal Antibody

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货号 TMAB-01072

别名 SMP2, RP4 620E11.3, Phosphatidate phosphatase LPIN3, LPIN3, LPIN 3, LIPN3L, Lipin-3-like, Lipin-3, Lipin3, Lipin 3 like, dJ620E11.2, dJ450M14.3, dJ450M14.2

Anti-Lipin 3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Lipin 3。Anti-Lipin 3 Polyclonal Antibody 可用于 ELISA,ICC/IF,IF,IHC-Fr,IHC-P,WB。

Anti-Lipin 3 Polyclonal Antibody

Anti-Lipin 3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-01072 别名 SMP2, RP4 620E11.3, Phosphatidate phosphatase LPIN3, LPIN3, LPIN 3, LIPN3L, Lipin-3-like, Lipin-3, Lipin3, Lipin 3 like, dJ620E11.2, dJ450M14.3, dJ450M14.2

Anti-Lipin 3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Lipin 3。Anti-Lipin 3 Polyclonal Antibody 可用于 ELISA,ICC/IF,IF,IHC-Fr,IHC-P,WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-Lipin 3 Polyclonal Antibody is a Rabbit antibody targeting Lipin 3. Anti-Lipin 3 Polyclonal Antibody can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P,WB.
别名SMP2, RP4 620E11.3, Phosphatidate phosphatase LPIN3, LPIN3, LPIN 3, LIPN3L, Lipin-3-like, Lipin-3, Lipin3, Lipin 3 like, dJ620E11.2, dJ450M14.3, dJ450M14.2
Ig Type
IgG
反应种属
(predicted:Human,Mouse,Rat,Rabbit)
应用ELISAICC/IFIFIHC-FrIHC-PWB
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Significant expression in intestine and other regions of the gastrointestinal tract.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Humans lipodystrophy is characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. Mice carrying mutations in the fatty liver dystrophy (fld) gene have similar phenotypes. Through positional cloning, the mouse gene responsible for fatty liver dystrophy was isolated and designated Lpin1. The nuclear protein encoded by Lpin1 was named lipin. Lpin1 mRNA was expressed at high levels in adipose tissue and was induced during differentiation of preadipocytes. These results indicated that lipin is required for normal adipose tissue development and provided a candidate gene for human lipodystrophy. Through database searches, mouse and human EST and genomic sequences with similarities to Lpin1 were identified. These included two related mouse genes (Lpin2 and Lpin3) and three human homologs (LPIN1, LPIN2, and LPIN3). Human LPIN1 gene has been mapped to 2p25.; linkages of fat mass and serum leptin levels to this same region have been noted. Human LPIN2 and LPIN3 mapped to chromosomes 18p11 and 20q11-q12, respectively. The mouse genes encoding Lpin1, Lpin2, and Lpin3 mapped to chromosome 12, 17, and 2, respectively. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human Lipin 3
抗原种属
Human
基因名称
LPIN3
基因ID
蛋白名称
Phosphatidate phosphatase LPIN3
Uniprot ID
功能
Regulates fatty acid metabolism. Magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis.
化学信息
分子量Theoretical: 94 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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