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Anti-GPX7 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GPX7。Anti-GPX7 Polyclonal Antibody 可用于 WB。
Anti-GPX7 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GPX7。Anti-GPX7 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-GPX7 Polyclonal Antibody is a Rabbit antibody targeting GPX7. Anti-GPX7 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat,Chicken,Cow,Rabbit,Monkey) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Expressed in esophageal epithelial cells; expression is up-regulated after exposure to acidic bile acids. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Glutathione peroxidase (GPx) enzymes are generally selenium-containing tetrameric glycoproteins that help prevent lipid peroxidation of cell membranes. GPx enzymes reduce lipid hydroperoxides to alcohols and reduce free hydrogen peroxide to water. GPx members are among the few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. There are eight GPx homologs (GPx-1–8). GPx-7 (glutathione peroxidase 7), also known as GPX6, CL683 or NPGPx, is a 187 amino acid secreted protein belonging to the glutathione peroxidase family. GPx-7 catalyzes the reaction of glutathione into glutathione disulfide and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. |
| 免疫原 | KLH conjugated synthetic peptide: human GPX7/Glutathione Peroxidase 7 |
| 抗原种属 | Human |
| 基因名称 | GPX7 |
| 基因ID | |
| 蛋白名称 | Glutathione peroxidase 7 |
| Uniprot ID | |
| 功能 | It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks. |
| 分子量 | Theoretical: 19 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |