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Anti-XAF1 Antibody (6H309)

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Anti-XAF1 Antibody (6H309)
产品编号 TMAC-04293
别名 XIAP-associated factor 1, XIAPAF1, XIAP associated factor 1, XAF1_HUMAN, XAF 1, HSXIAPAF1, HSXIAPAF 1, BIRC4BP, BIRC4-binding protein, BIRC4 binding protein, BIRC 4 binding protein

Anti-XAF1 Antibody (6H309) 是一种 Mouse 抗体，靶向 XAF1。Anti-XAF1 Antibody (6H309) 可用于 WB,IP,IF。

Anti-XAF1 Antibody (6H309)

Anti-XAF1 Antibody (6H309)

Rating icon 还可以
Anti-XAF1 Antibody (6H309)
产品编号 TMAC-04293 别名 XIAP-associated factor 1, XIAPAF1, XIAP associated factor 1, XAF1_HUMAN, XAF 1, HSXIAPAF1, HSXIAPAF 1, BIRC4BP, BIRC4-binding protein, BIRC4 binding protein, BIRC 4 binding protein

Anti-XAF1 Antibody (6H309) 是一种 Mouse 抗体，靶向 XAF1。Anti-XAF1 Antibody (6H309) 可用于 WB,IP,IF。

规格价格库存数量
50 μL
¥ 1,980
5日内发货
100 μL
¥ 2,990
5日内发货
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产品介绍

生物活性
产品描述
Anti-XAF1 Antibody (6H309) is a Mouse antibody targeting XAF1. Anti-XAF1 Antibody (6H309) can be used in WB,IP,IF.
别名XIAP-associated factor 1, XIAPAF1, XIAP associated factor 1, XAF1_HUMAN, XAF 1, HSXIAPAF1, HSXIAPAF 1, BIRC4BP, BIRC4-binding protein, BIRC4 binding protein, BIRC 4 binding protein
交叉反应
Human
验证活性
1. Western blot analysis of XAF1 expression in non-transfected (A) and human XAF1 transfected (B) 293T whole cell lysates.
应用
WB
IP
IF
推荐剂量
WB: 1:100-1000; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景X-linked inhibitor of apoptosis protein (XIAP)-associated factor 1 (XAF1) is azinc finger protein that blocks the apoptotic activity of XIAP. XIAP is amember of the family of intrinsic inhibitors of apoptosis proteins (IAPs), whichsuppress apoptosis through the inhibition of caspases. In the presence ofXAF1, XIAP protein redistributes from the cytosol to the nucleus. XAF1 transcripts(3.9-, 4.5-, 6.0- and 7.0-kb) are present at high levels in heart and ovary.Low expression of XAF1 mRNA is an indicator for certain cancers (WM164melanoma, WM35 melanoma, U937 pro-monocytic leukemia and HT1080fibrosarcoma), suggesting that low levels of XAF1 transcript may enhancecancer cell-survival through the relative increase in XIAP apoptotic function.IFN-α and IFN-β activate the human XAF1 gene, which maps to chromosome17p13.1.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Amino acids 1-225 mapping at the N-terminus of XAF1 of human origin
抗原种属
human
Uniprot ID
Q6GPH4
化学信息
分子量Theoretical: 35 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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