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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-DAZ4 Polyclonal Antibody

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货号 TMAB-04989

Anti-DAZ4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DAZ4。Anti-DAZ4 Polyclonal Antibody 可用于 WB。

Anti-DAZ4 Polyclonal Antibody

Anti-DAZ4 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-04989

Anti-DAZ4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DAZ4。Anti-DAZ4 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-DAZ4 Polyclonal Antibody is a Rabbit antibody targeting DAZ4. Anti-DAZ4 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Spermatogenesis is the process by which male spermatogonia develop into mature spermatozoa. DAZ (deleted in azoospermia) are RNA-binding proteins that play an essential role in spermatogenesis. DAZ proteins influence the first stages of spermatogenesis and the maintenance of germ cell populations. DAZ proteins (DAZ1, DAZ2, DAZ3, DAZ4 and DAZ5) are encoded by separate genes on chromosome Y, each of which contain an AZFc domain in their coding region. DAZ proteins localize to the nucleus of spermatogonia, but relocate to the cytoplasm during meiosis. DAZ proteins contain an RRM (RNA recognition motif) domain that may regulate mRNA translation by binding to the 3’UTR. Deletions in the genes encoding DAZ proteins may cause azoospermia or oligospermia which can lead to male infertility. DAZ4 (deleted in azoospermia 4), also known as pDP1680 or pDP1681, is a 579 amino acid testis specific protein that contains nine DAZ-like domains and two RNA recognition motifs (RRM). DAZ4 exists as two alternatively spliced isoforms.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DAZ4
抗原种属
Human
基因名称
DAZ4
基因ID
57135
蛋白名称
Deleted in azoospermia protein 4
Uniprot ID
Q86SG3
功能
Deleted in azoospermia 4 is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that plays an essential role in spermatogenesis. It may act by binding to the 3'-UTR of mRNAs and regulating their translation.
化学信息
分子量Theoretical: 65 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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