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Anti-Neuroligin-1 Antibody (8J729)

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产品编号 TMAY-01939

Anti-Neuroligin-1 Antibody (8J729) 是一种 Rabbit 抗体,靶向 Neuroligin-1。Anti-Neuroligin-1 Antibody (8J729) 可用于 ELISA。

Anti-Neuroligin-1 Antibody (8J729)

Anti-Neuroligin-1 Antibody (8J729)

Rating icon 还可以
产品编号 TMAY-01939

Anti-Neuroligin-1 Antibody (8J729) 是一种 Rabbit 抗体,靶向 Neuroligin-1。Anti-Neuroligin-1 Antibody (8J729) 可用于 ELISA。

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产品介绍

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产品描述
Anti-Neuroligin-1 Antibody (8J729) is a Rabbit antibody targeting Neuroligin-1. Anti-Neuroligin-1 Antibody (8J729) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
8J729
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human Neuroligin 1 / NLGN1 (rh Neuroligin 1 / NLGN1; TMPY-01726; NP_055747.1; Met1-Ser677).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Neuroligin 1 (NLGN1) belongs to the type-B carboxylesterase/lipase family, is a synaptic cell-adhesion molecule that is enriched in postsynaptic densities where it may recruit receptors, channels, and signal-transduction molecules to synaptic sites of cell adhesion. Neuroligins consists of five members (NLGN1, NLGN2, NLGN3, NLGN4, and NLGN4Y), which interact with beta-neurexins, and this interaction is involved in the formation of functional synapses. The extracellular domain of functional Neuroligin 1 associates as a dimer when analyzed by sedimentation equilibrium. Neuroligin 1 has a unique N-linked glycosylation pattern in the neuroligin family, and glycosylation and its processing modify neuroligin activity. Neuroligin 1 is a potent trigger for the de novo formation of synaptic connections, and it has recently been suggested that it is required for the maturation of functionally competent excitatory synapses. The persistent expression of Neuroligin 1 is required for the maintenance of NMDAR-mediated synaptic transmission, which enables the normal development of synaptic plasticity and long-term memory in the amygdala of adult animals.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human Neuroligin 1 / NLGN1 protein (TMPY-01726)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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