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Anti-DNAH1 Polyclonal Antibody

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货号 TMAB-05223

Anti-DNAH1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 DNAH1。Anti-DNAH1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-DNAH1 Polyclonal Antibody

Anti-DNAH1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05223

Anti-DNAH1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 DNAH1。Anti-DNAH1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-DNAH1 Polyclonal Antibody is a Rabbit antibody targeting DNAH1. Anti-DNAH1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Pig,Cow,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm > cytoskeleton > cilium axoneme.
组织特异性Expressed primarily in trachea and testis, 2 tissues containing axonemal structures. Also expressed in brain.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Axonemal Dynein motors contain one to three non-identical heavy chains and cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia to beat and propel the cell. DNAH1 (dynein heavy chain 1, axonemal), also known as heat shock regulated protein 1 or ciliary dynein heavy chain 1, is a 4,330 amino acid protein consisting of at least two heavy chains and several intermediate and light chains. Mutations in the gene encoding DNAH1 may be a cause of primary ciliary dyskinesia, also known as Kartagener Syndrome, which is characterized by chronic recurrent respiratory infections due to defective cilia action in the respiratory tract. There are three isoforms of DNAH1 that exist as a result of alternative splicing events.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DNAH1
抗原种属
Human
基因名称
DNAH1
基因ID
蛋白名称
Dynein heavy chain 1, axonemal
Uniprot ID
功能
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly.
化学信息
分子量Theoretical: 494 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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