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IL-10 Protein, Human, Recombinant V2

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产品编号 TMPY-03547U

IL-10 Protein, Human, Recombinant V2 is expressed in HEK293 Cells. The accession number is P22301.

IL-10 Protein, Human, Recombinant V2

一键复制产品信息

产品编号 TMPY-03547U

IL-10 Protein, Human, Recombinant V2 is expressed in HEK293 Cells. The accession number is P22301.

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产品信息

生物活性	Immobilized Human IL-10, No Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Human IL-10 R alpha, His Tag with the EC50 of 21.8 ng/ml determined by ELISA (QC Test). Human IL-10 R alpha, His Tag captured on CM5 Chip via Anti-His Antibody can bind Human IL-10, No Tag with an affinity constant of 0.255 nM as determined in SPR assay (Biacore T200).
产品描述	IL-10 Protein, Human, Recombinant V2 is expressed in HEK293 Cells. The accession number is P22301.
种属	Human
表达系统	HEK293 Cells
标签	Tag Free
蛋白编号	P22301
别名	白细胞介素,TGIF,Interleukin-10,interleukin 10,IL10A,IL-10,GVHDS,CSIF
蛋白构建	Ser19-Asn178
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	18.8 kDa (Predicted and reducing conditions)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Interleukin 10 (IL10) is a key anti-inflammatory cytokine that can inhibit proinflammatory responses of both innate and adaptive immune cells. An association between IL10 and intestinal mucosal homeostasis became clear with the discovery that IL10 and IL10 receptor (IL10R)-deficient mice develop spontaneous intestinal inflammation. Similarly, patients with deleterious mutations in IL10, IL10RA, or IL10RB present with severe enterocolitis within the first months of life.