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Anti-C-MPL Antibody (1H828)

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Anti-C-MPL Antibody (1H828)
产品编号 TMAC-02642
别名 TPOR, THCYT2, MPLV, MPL proto-oncogene, thrombopoietin receptor, C-MPL, CD110

Anti-C-MPL Antibody (1H828) 是一种 Mouse 抗体,靶向 C-MPL。Anti-C-MPL Antibody (1H828) 可用于 WB,FCM。

Anti-C-MPL Antibody (1H828)

Anti-C-MPL Antibody (1H828)

Rating icon 还可以
Anti-C-MPL Antibody (1H828)
产品编号 TMAC-02642 别名 TPOR, THCYT2, MPLV, MPL proto-oncogene, thrombopoietin receptor, C-MPL, CD110

Anti-C-MPL Antibody (1H828) 是一种 Mouse 抗体,靶向 C-MPL。Anti-C-MPL Antibody (1H828) 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,985
5日内发货
100 μL
¥ 2,995
5日内发货
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产品介绍

生物活性
产品描述
Anti-C-MPL Antibody (1H828) is a Mouse antibody targeting C-MPL. Anti-C-MPL Antibody (1H828) can be used in WB,FCM.
别名TPOR, THCYT2, MPLV, MPL proto-oncogene, thrombopoietin receptor, C-MPL, CD110
交叉反应
Human
验证活性
1. Western blot analysis of MPL on human MPL recombinant protein using anti-MPL antibody at 1/1,000 dilution.
2. Flow cytometric analysis of MOLT4 cells with MPL antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
应用
推荐剂量
WB: 1:500-1000; FCM: 1:100-200
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
研究背景Thrombopoietin was shown to be the major regulator of megakaryocytopoiesis and platelet formation. The protein encoded by the c-mpl gene, CD110, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs . TPO-R deficient mice were severely thrombocytopenic, emphasizing the important role of CD110 and thrombopoietin in megakaryocyte and platelet formation. Upon binding of thrombopoietin CD110 is dimerized and the JAK family of non-receptor tyrosine kinases, as well as the STAT family, the MAPK family, the adaptor protein Shc and the receptors themselves become tyrosine phosphorylated.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 71 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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