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Anti-C-MPL Antibody (1H828) 是一种 Mouse 抗体,靶向 C-MPL。Anti-C-MPL Antibody (1H828) 可用于 WB,FCM。
Anti-C-MPL Antibody (1H828) 是一种 Mouse 抗体,靶向 C-MPL。Anti-C-MPL Antibody (1H828) 可用于 WB,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,985 | 5日内发货 | |
100 μL | ¥ 2,995 | 5日内发货 |
产品描述 | Anti-C-MPL Antibody (1H828) is a Mouse antibody targeting C-MPL. Anti-C-MPL Antibody (1H828) can be used in WB,FCM. |
别名 | TPOR, THCYT2, MPLV, MPL proto-oncogene, thrombopoietin receptor, C-MPL, CD110 |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of MPL on human MPL recombinant protein using anti-MPL antibody at 1/1,000 dilution. 2. Flow cytometric analysis of MOLT4 cells with MPL antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
应用 | |
推荐剂量 | WB: 1:500-1000; FCM: 1:100-200 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
研究背景 | Thrombopoietin was shown to be the major regulator of megakaryocytopoiesis and platelet formation. The protein encoded by the c-mpl gene, CD110, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs . TPO-R deficient mice were severely thrombocytopenic, emphasizing the important role of CD110 and thrombopoietin in megakaryocyte and platelet formation. Upon binding of thrombopoietin CD110 is dimerized and the JAK family of non-receptor tyrosine kinases, as well as the STAT family, the MAPK family, the adaptor protein Shc and the receptors themselves become tyrosine phosphorylated. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 71 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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