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Anti-ICAM-1/CD54 Antibody (2M737)

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货号 TMAC-02082

别名 P3.58, intercellular adhesion molecule 1, ICAM-1, CD54, BB2

Anti-ICAM-1/CD54 Antibody (2M737) 是一种 Rabbit 抗体,靶向 ICAM-1/CD54。Anti-ICAM-1/CD54 Antibody (2M737) 可用于 ICC/IF,IHC,WB。

Anti-ICAM-1/CD54 Antibody (2M737)

Anti-ICAM-1/CD54 Antibody (2M737)

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Rating icon 还可以
货号 TMAC-02082 别名 P3.58, intercellular adhesion molecule 1, ICAM-1, CD54, BB2

Anti-ICAM-1/CD54 Antibody (2M737) 是一种 Rabbit 抗体,靶向 ICAM-1/CD54。Anti-ICAM-1/CD54 Antibody (2M737) 可用于 ICC/IF,IHC,WB。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍


生物活性
产品描述
Anti-ICAM-1/CD54 Antibody (2M737) is a Rabbit antibody targeting ICAM-1/CD54. Anti-ICAM-1/CD54 Antibody (2M737) can be used in ICC/IF,IHC,WB.
别名P3.58, intercellular adhesion molecule 1, ICAM-1, CD54, BB2
Ig Type
IgG
克隆号
2M737
反应种属
Human
验证活性
1. Western blot analysis of ICAM1 on different lysates using anti-ICAM1 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: HUVEC, Lane 3: Raji.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-ICAM1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-ICAM1 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-ICAM1 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-ICAM1 antibody. Counter stained with hematoxylin.
6. ICC staining ICAM1 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. ICC staining ICAM1 in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
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应用ICC/IFIHCWB
推荐剂量
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Cell adhesion molecules (CAMs) are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play important, yet separate, roles in embryogenesis and development. The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily and recognizes the beta2alpha1 and beta2alphaM Integrins. ICAM-2 functions as a ligand for lymphocyte function-associated antigen-1 (LFA-1) and is involved in leukocyte adhesion. ICAM-3 is highly expressed on the surface of human eosinophils and, when bound to ligand, may inhibit eosinophil inflammatory responses and survival. ICAM-4, also known as LW glycoprotein, interacts with Integrins alphaLbeta2, alphaMbeta2, alpha4beta1, the alphaV family and alphaIIbbeta3, and selective binding to different integrins may be relevant to the pathology in a number of red blood cell associated diseases. Lastly, ICAM-5, expressed on telencephalic neurons, binds CD11a/CD18 and thus may act as an adhesion molecule for leukocyte binding in the central nervous system.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 89 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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