Anti-NGF Antibody (6U823)

Name: Anti-NGF Antibody (6U823)
Brand: TargetMol
SKU: TMAH-00817
Rating: 4.5 (1 reviews)

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产品编号 TMAH-00817

别名 神经生长因子, β-NGF, NGFB, nerve growth factor (β polypeptide), nerve growth factor (beta polypeptide), HSAN5, Beta-NGF

Anti-NGF Antibody (6U823) 是一种抗体，靶向 NGF。Anti-NGF Antibody (6U823) 可用于 ELISA, FC。

Anti-NGF Antibody (6U823)

还可以

产品编号 TMAH-00817 别名 神经生长因子, β-NGF, NGFB, nerve growth factor (β polypeptide), nerve growth factor (beta polypeptide), HSAN5, Beta-NGF

Anti-NGF Antibody (6U823) 是一种抗体，靶向 NGF。Anti-NGF Antibody (6U823) 可用于 ELISA, FC。

规格	价格	库存	数量
50 μL	¥ 1,310	5日内发货
100 μL	¥ 2,180	5日内发货

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产品描述	Anti-NGF Antibody (6U823) is an antibody targeting NGF. Anti-NGF Antibody (6U823) can be used in ELISA, FC.
别名	神经生长因子, β-NGF, NGFB, nerve growth factor (β polypeptide), nerve growth factor (beta polypeptide), HSAN5, Beta-NGF
Ig Type	hIgG2
克隆号	6U823
交叉反应	Human
验证活性	Overlay Peak curve showing PC3 cells stained with TMAH-00817 (red line) at 1:100. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/110^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-human IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was human IgG (1ug/110^6 cells) used under the same conditions. Acquisition of >10,000 events was performed.
应用	ELISA, FC
推荐剂量	FC:1:50-1:200.
抗体种类	Monoclonal
亚细胞定位	Secreted. Endosome lumen.
构建方式	Recombinant Antibody
纯化方式	Affinity-chromatography
性状	Liquid
缓冲液	Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
研究背景	Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (Probable). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone collapse. In contrast to mature NGF, the precursor form (proNGF) promotes neuronal apoptosis (in vitro). Inhibits metalloproteinase-dependent proteolysis of platelet glycoprotein VI. Binds lysophosphatidylinositol and lysophosphatidylserine between the two chains of the homodimer. The lipid-bound form promotes histamine relase from mast cells, contrary to the lipid-free form.