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IL-29 Protein, Human, Recombinant

IL-29 Protein, Human, Recombinant

产品编号 TMPY-00136
别名: interferon, λ1, IL-29, IL29, interferon, lambda 1, IFNL1, 白介素, 白细胞介素

IL-29 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.2 kDa and the accession number is A0A7R8C391.

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IL-29 Protein, Human, Recombinant
规格 价格/CNY 货期 数量
20 μg ¥ 1,050 现货
100 μg ¥ 2,930 5日内发货
200 μg ¥ 5,220 5日内发货
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产品目录号及名称: IL-29 Protein, Human, Recombinant (TMPY-00136)
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生物活性
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产品性质
参考文献
生物活性 Measured in antiviral assays using HepG2 cells infected with vesicular stomatitis virus. The ED50 for this effect is typically 10-39 ng/mL.

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产品描述 IL-29 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.2 kDa and the accession number is A0A7R8C391.
种属 Human
表达系统 HEK293 Cells
标签 Tag Free
蛋白编号 A0A7R8C391
别名 interferon, λ1, IL-29, IL29, interferon, lambda 1, IFNL1, 白介素, 白细胞介素
蛋白构建 The Human IFNL1 (NP_742152.1) (Met1-Thr200) was expressed with an initial Met.
蛋白纯度 > 95 % as determined by SDS-PAGE

TargetMol

分子量 20.2 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 Interleukin-29 (IL-29), also known as cytokine Zcyto21, Interferon lambda-1, IFN-lambda-1, and IFNL1, is a secreted protein that belongs to the IL-28 / IL-29 family. IL-29 is a cytokine with immunomodulatory activity. IL-29 is highly similar in amino acid sequence to the IL-28. IL-28 and IL-29 are induced by a viral infection and showed antiviral activity. IL-28 and IL-29 interacted with a heterodimeric class II cytokine receptor that consisted of IL-10 receptor beta (IL-10Rbeta) and an orphan class II receptor chain, designated IL-28Ralpha. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. IL-29 may play a role in antiviral immunity. IL-29 up-regulates MHC class I antigen expression. It is a Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

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Keywords

IL-29 Protein, Human, Recombinant interferon, λ1 IL-29 IL 29 IL29 interferon, lambda 1 IFNL1 白介素 IFNL 1 IFNL-1 白细胞介素 recombinant recombinant-proteins proteins protein

 

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