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IL-29 Protein, Human, Recombinant

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产品编号 TMPY-00136

IL-29 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.2 kDa and the accession number is A0A7R8C391.

IL-29 Protein, Human, Recombinant

一键复制产品信息

产品编号 TMPY-00136

IL-29 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.2 kDa and the accession number is A0A7R8C391.

规格	价格	库存
5 μg	¥ 396	6-8日内发货
10 μg	¥ 638	6-8日内发货
20 μg	¥ 1,050	In stock
50 μg	¥ 1,870	5日内发货
100 μg	¥ 2,930	5日内发货
200 μg	¥ 5,220	5日内发货

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产品信息

生物活性	Measured in antiviral assays using HepG2 cells infected with vesicular stomatitis virus. The ED50 for this effect is typically 10-39 ng/mL.
产品描述	IL-29 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.2 kDa and the accession number is A0A7R8C391.
种属	Human
表达系统	HEK293 Cells
标签	Tag Free
蛋白编号	Q8IU54
别名	白细胞介素,白介素,interferon, λ1,interferon, lambda 1,IL-29,IL29,IFNL1
蛋白构建	A DNA sequence encoding the human IFNL1 (NP_742152.1) (Met1-Thr200) was expressed with an initial Met. Predicted N terminal: Met
蛋白纯度	> 95 % as determined by SDS-PAGE
分子量	20.2 kDa (predicted)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Interleukin-29 (IL-29), also known as cytokine Zcyto21, Interferon lambda-1, IFN-lambda-1, and IFNL1, is a secreted protein that belongs to the IL-28 / IL-29 family. IL-29 is a cytokine with immunomodulatory activity. IL-29 is highly similar in amino acid sequence to the IL-28. IL-28 and IL-29 are induced by a viral infection and showed antiviral activity. IL-28 and IL-29 interacted with a heterodimeric class II cytokine receptor that consisted of IL-10 receptor beta (IL-10Rbeta) and an orphan class II receptor chain, designated IL-28Ralpha. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. IL-29 may play a role in antiviral immunity. IL-29 up-regulates MHC class I antigen expression. It is a Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.