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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-BCL10 Polyclonal Antibody

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货号 TMAB-03046

Anti-BCL10 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 BCL10。Anti-BCL10 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM,ICC/IF。

Anti-BCL10 Polyclonal Antibody

Anti-BCL10 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-03046

Anti-BCL10 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 BCL10。Anti-BCL10 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM,ICC/IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-BCL10 Polyclonal Antibody is a Rabbit antibody targeting BCL10. Anti-BCL10 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM,ICC/IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIFFCMICC/IF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test; ICC/IF: 1:50-200
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm > perinuclear region. Membrane raft. Appears to have a perinuclear, compact and filamentous pattern of expression. Also found in the nucleus of several types of tumor cells. Colocalized with DPP4 in membrane rafts.
组织特异性Ubiquitous.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human Bcl-10
抗原种属
Human
基因名称
BCL10
基因ID
8915
蛋白名称
B-cell lymphoma/leukemia 10
Uniprot ID
O95999
功能
Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1.
化学信息
分子量Theoretical: 26 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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