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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Integrin beta 5 Polyclonal Antibody

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货号 TMAB-07753

Anti-Integrin beta 5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Integrin beta 5。Anti-Integrin beta 5 Polyclonal Antibody 可用于 WB。

Anti-Integrin beta 5 Polyclonal Antibody

Anti-Integrin beta 5 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-07753

Anti-Integrin beta 5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Integrin beta 5。Anti-Integrin beta 5 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Integrin beta 5 Polyclonal Antibody is a Rabbit antibody targeting Integrin beta 5. Anti-Integrin beta 5 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around 22 different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function. The integrin subunit beta 5 has only been associated with the alpha v subunit to form the alpha v beta 5 heterodimer. This integrin mediates cell adhesion to vitronectin and also recognizes fibronectin when the integrin is activated. This integrin is found in a variety of cells in most normal tissue.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Integrin beta 5
抗原种属
Human
基因名称
ITGB5
基因ID
3693
蛋白名称
Integrin beta-5
Uniprot ID
P18084
功能
Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.
化学信息
分子量Theoretical: 86 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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