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Anti-Stabilin-1 Polyclonal Antibody

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产品编号 TMAB-01777

别名 Stabilin-1, STAB1, MS-1 antigen, KIAA0246, FEEL1, Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1 (FEEL-1)

Anti-Stabilin-1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Stabilin-1。Anti-Stabilin-1 Polyclonal Antibody 可用于 ICC/IF,IF,IHC-Fr,IHC-P,WB。

Anti-Stabilin-1 Polyclonal Antibody

Anti-Stabilin-1 Polyclonal Antibody

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Rating icon 还可以
产品编号 TMAB-01777 别名 Stabilin-1, STAB1, MS-1 antigen, KIAA0246, FEEL1, Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1 (FEEL-1)

Anti-Stabilin-1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Stabilin-1。Anti-Stabilin-1 Polyclonal Antibody 可用于 ICC/IF,IF,IHC-Fr,IHC-P,WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Stabilin-1 Polyclonal Antibody is a Rabbit antibody targeting Stabilin-1. Anti-Stabilin-1 Polyclonal Antibody can be used in ICC/IF,IF,IHC-Fr,IHC-P,WB.
别名Stabilin-1, STAB1, MS-1 antigen, KIAA0246, FEEL1, Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1 (FEEL-1)
Ig Type
IgG
交叉反应
Mouse (predicted:Horse,Cow,Rat,Human)
应用ICC/IFIFIHC-FrIHC-PWB
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
组织特异性High levels found in spleen, lymph node, liver and placenta. Also expressed in endothelial cells.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Stabilin-1 is a large transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes.
抗原信息
免疫原
KLH conjugated synthetic peptide: human stabilin1
抗原种属
Human
基因名称
STAB1
基因ID
蛋白名称
Stabilin-1
Uniprot ID
功能
Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system.
化学信息
分子量Theoretical: 273 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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