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别名 Stabilin-1, STAB1, MS-1 antigen, KIAA0246, FEEL1, Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1 (FEEL-1)
Anti-Stabilin-1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Stabilin-1。Anti-Stabilin-1 Polyclonal Antibody 可用于 ICC/IF,IF,IHC-Fr,IHC-P,WB。
Anti-Stabilin-1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Stabilin-1。Anti-Stabilin-1 Polyclonal Antibody 可用于 ICC/IF,IF,IHC-Fr,IHC-P,WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-Stabilin-1 Polyclonal Antibody is a Rabbit antibody targeting Stabilin-1. Anti-Stabilin-1 Polyclonal Antibody can be used in ICC/IF,IF,IHC-Fr,IHC-P,WB. |
| 别名 | Stabilin-1, STAB1, MS-1 antigen, KIAA0246, FEEL1, Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1 (FEEL-1) |
| Ig Type | IgG |
| 交叉反应 | Mouse (predicted:Horse,Cow,Rat,Human) |
| 应用 | ICC/IFIFIHC-FrIHC-PWB |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | High levels found in spleen, lymph node, liver and placenta. Also expressed in endothelial cells. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | Stabilin-1 is a large transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes. |
| 免疫原 | KLH conjugated synthetic peptide: human stabilin1 |
| 抗原种属 | Human |
| 基因名称 | STAB1 |
| 基因ID | |
| 蛋白名称 | Stabilin-1 |
| Uniprot ID | |
| 功能 | Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system. |
| 分子量 | Theoretical: 273 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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