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Anti-IL-17A Antibody (9L713)

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Anti-IL-17A Antibody (9L713)
产品编号 TMAY-03535
别名 interleukin 17A

Anti-IL-17A Antibody (9L713) 是一种 Rabbit 抗体，靶向 IL-17A。Anti-IL-17A Antibody (9L713) 可用于 FCM。

Anti-IL-17A Antibody (9L713)
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Anti-IL-17A Antibody (9L713)

Rating icon 还可以
Anti-IL-17A Antibody (9L713)
产品编号 TMAY-03535 别名 interleukin 17A

Anti-IL-17A Antibody (9L713) 是一种 Rabbit 抗体，靶向 IL-17A。Anti-IL-17A Antibody (9L713) 可用于 FCM。

规格价格库存数量
100 μL
¥ 2,284
5日内发货
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产品介绍

生物活性
产品描述
Anti-IL-17A Antibody (9L713) is a Rabbit antibody targeting IL-17A. Anti-IL-17A Antibody (9L713) can be used in FCM.
别名interleukin 17A
Ig Type
Rabbit IgG
克隆号
9L713
交叉反应
Mouse
验证活性
Flow cytometric analysis of Mouse IL17 expression on EL4 cells.The cells were stimulated for 4-6 hours with PMA and Ionomycin in the presence of GolgiPlug. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Mouse IL17, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用
FCM
推荐剂量
FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL-17A (rM IL-17A; TMPY-02900; Q62386; Thr22-Ala158).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. The IL-17 family of cytokines includes six members, IL-17/IL-17A, IL-17B, IL-17C, IL-17D, IL-17E/IL-25, and IL-17F, which are produced by multiple cell types. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis, and multiple sclerosis.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
其他可选修饰符
APC/FITC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Protein: Mouse IL-17A Protein (TMPY-02900)
抗原种属
Mouse
研究领域
Neuroinflammation
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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