MKK6 Protein, Human, Recombinant (S207D, T211D) is expressed in Baculovirus insect cells. The predicted molecular weight is 37.7 kDa and the accession number is P52564-1.
生物活性 | Kinase activity untested |
产品描述 | MKK6 Protein, Human, Recombinant (S207D, T211D) is expressed in Baculovirus insect cells. The predicted molecular weight is 37.7 kDa and the accession number is P52564-1. |
种属 | Human |
表达系统 | Baculovirus Insect Cells |
标签 | Tag Free |
蛋白编号 | P52564-1 |
别名 | MAPKK6, PRKMK6, MKK6, MEK6, mitogen-activated protein kinase kinase 6, SAPKK-3, SAPKK3 |
蛋白构建 | The Human MAP2K6 (P52564-1) (Met 1-Asp 334, 207Asp, 211Asp) was expressed and purified with two additional amino acids (Gly & Pro ) at the N-terminus. |
蛋白纯度 | > 85 % as determined by SDS-PAGE |
分子量 | 37.7 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Supplied as sterile 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 8.0. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store the product under sterile conditions at -20℃ to -80℃. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice. |
研究背景 | Dual specificity mitogen-activated protein kinase kinase 6, also known as MAP kinase kinase 6, MAPKK 6, MAPK / ERK kinase 6, SAPKK3, MAP2K6, and MKK6, is a protein that belongs to the protein kinase superfamily, STE Ser / Thr protein kinase family and MAP kinase kinase subfamily. MAP2K6 / MKK6 contains one protein kinase domain. Mitogen-activated protein kinases are members of a conserved cascade of kinases involved in many signal transduction pathways. They stimulate phosphorylation of transcription factors in response to extracellular signals such as growth factors, cytokines, ultraviolet light, and stress-inducing agents. MAP2K6 / MKK6 exists in a variety of alternatively spliced isoforms with distinct patterns of tissue expression. Isoform 2 of MAP2K6 / MKK6 is only expressed in skeletal muscle. Isoform 1 of MAP2K6 / MKK6 is expressed in skeletal muscle, heart, and to a lesser extent in liver or pancreas. |
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MKK6 Protein, Human, Recombinant (S207D, T211D) MAPKK6 MEK-6 MAPKK 6 PRKMK6 MKK6 MEK6 PRKMK-6 mitogen-activated protein kinase kinase 6 MKK 6 SAPKK-3 MKK-6 SAPKK 3 MAPKK-6 SAPKK3 MEK 6 PRKMK 6 recombinant recombinant-proteins proteins protein