Anti-HGF Antibody (5U533)

Name: Anti-HGF Antibody (5U533)
Brand: TargetMol
SKU: TMAY-03665
Rating: 4.5 (1 reviews)

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产品编号 TMAY-03665

Anti-HGF Antibody (5U533) 是一种 Rabbit 抗体，靶向 HGF。Anti-HGF Antibody (5U533) 可用于 ELISA。

Anti-HGF Antibody (5U533)

还可以

产品编号 TMAY-03665

Anti-HGF Antibody (5U533) 是一种 Rabbit 抗体，靶向 HGF。Anti-HGF Antibody (5U533) 可用于 ELISA。

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产品描述	Anti-HGF Antibody (5U533) is a Rabbit antibody targeting HGF. Anti-HGF Antibody (5U533) can be used in ELISA.
Ig Type	Monoclonal Rabbit IgG
克隆号	5U533
交叉反应	Canine
应用	ELISA
推荐剂量	ELISA: 1:5000-1:10000
抗体种类	Monoclonal
宿主来源	Rabbit
构建方式	This antibody was obtained from a rabbit immunized with purified, recombinant Canine HGF/Hepatocyte Growth Factor ( TMPY-00456; NP_001002964.1; Met1-Ser730).
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	Hepatocyte growth factor, also known as HGF, contains 4 kringle domains, 1 PAN domain, and 1 peptidase S1 domain. It belongs to the peptidase S1 family, plasminogen subfamily. The hepatocyte growth factor is secreted by mesenchymal cells as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor, and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility and matrix invasion give it a central role in angiogenesis, tumorogenesis, and tissue regeneration. HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. HGF has no detectable protease activity. Defects in hepatocyte growth factor are the cause of deafness autosomal recessive type 39. A form of profound prelingual sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Canine HGF/Hepatocyte Growth Factor Protein (TMPY-00456)
抗原种属	Canine
研究领域	Cancer Drug Targets

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.