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GAS6 Protein, Human, Recombinant (hFc)

GAS6 Protein, Human, Recombinant (hFc)

产品编号 TMPJ-00366
别名: AXLLG, Gas6, GAS-6, AXLLGAXL stimulatory factor, growth arrest-specific protein 6, AXSFAXL receptor tyrosine kinase ligand, growth arrest-specific 6

GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

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GAS6 Protein, Human, Recombinant (hFc)
规格 价格/CNY 货期 数量
10 μg ¥ 1,070 5日内发货
50 μg ¥ 3,250 5日内发货
500 μg ¥ 15,200 5日内发货
1 mg ¥ 22,800 5日内发货
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产品目录号及名称: GAS6 Protein, Human, Recombinant (hFc) (TMPJ-00366)
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生物活性
技术参数
产品性质
生物活性 1. Loaded Mouse AXL-His on HIS1K Biosensor, can bind Human GAS6-Fc with an affinity constant of 0.006 nM as determined in BLI assay. (Regularly tested) 2. Immobilized Human AXL-His at 5μg/ml (100 μl/well) can bind Human GAS6-Fc. The ED50 of Human GAS6-Fc is 55.16 ng/ml. (Regularly tested)
产品描述 GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
种属 Human
表达系统 HEK293 Cells
标签 C-hFc
蛋白编号 Q14393
别名 AXLLG, Gas6, GAS-6, AXLLGAXL stimulatory factor, growth arrest-specific protein 6, AXSFAXL receptor tyrosine kinase ligand, growth arrest-specific 6
氨基酸序列 Ala31-Ala678
蛋白构建 Ala31-Ala678
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 110-120 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

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Keywords

GAS6 Protein, Human, Recombinant (hFc) AXLLG Gas6 GAS-6 GAS6 AXLLGAXL stimulatory factor growth arrest-specific protein 6 AXSFAXL receptor tyrosine kinase ligand growth arrest-specific 6 GAS 6 recombinant recombinant-proteins proteins protein

 

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