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Anti-KIR2DL4 Antibody (1X510)

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货号 TMAY-02442

别名 KIR-2DL4, KIR2DL4, KIR-103AS, KIR103AS, KIR103, KIR, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4, G9P, CD158D

Anti-KIR2DL4 Antibody (1X510) 是一种 Mouse 抗体,靶向 KIR2DL4。Anti-KIR2DL4 Antibody (1X510) 可用于 ELISA。

Anti-KIR2DL4 Antibody (1X510)

Anti-KIR2DL4 Antibody (1X510)

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Rating icon 还可以
货号 TMAY-02442 别名 KIR-2DL4, KIR2DL4, KIR-103AS, KIR103AS, KIR103, KIR, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4, G9P, CD158D

Anti-KIR2DL4 Antibody (1X510) 是一种 Mouse 抗体,靶向 KIR2DL4。Anti-KIR2DL4 Antibody (1X510) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 1,679
5日内发货
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产品介绍


生物活性
产品描述
Anti-KIR2DL4 Antibody (1X510) is a Mouse antibody targeting KIR2DL4. Anti-KIR2DL4 Antibody (1X510) can be used in ELISA.
别名KIR-2DL4, KIR2DL4, KIR-103AS, KIR103AS, KIR103, KIR, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4, G9P, CD158D
Ig Type
Mouse IgG1
克隆号
1X510
反应种属
Human
特异性
Human KIR2DL4
应用ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human KIR2DL4 / CD158D (rh KIR2DL4 / CD158D; TMPY-03652; ADY38409.1; Met1-His242). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景KIR2DL4, also known as CD158d, is a member of the killer cell Ig-like receptor (KIR) family. KIRs are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of KIR2DL4 was sensitive to inhibition by another ITIM-containing receptor. The activation-deficient mutant of KIR2DL4 inhibited the signal delivered by the activating receptor CD16.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human KIR2DL4 / CD158D Protein (TMPY-03652)
抗原种属
Human
研究领域
ITIM/ITAM Immunoreceptors and Related Molecules
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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