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Anti-KIR2DL4 Antibody (1X510)
还可以产品编号 TMAY-02442
Anti-KIR2DL4 Antibody (1X510) 是一种 Mouse 抗体，靶向 KIR2DL4。Anti-KIR2DL4 Antibody (1X510) 可用于 ELISA。
Anti-KIR2DL4 Antibody (1X510)
Anti-KIR2DL4 Antibody (1X510)
还可以产品编号 TMAY-02442
Anti-KIR2DL4 Antibody (1X510) 是一种 Mouse 抗体，靶向 KIR2DL4。Anti-KIR2DL4 Antibody (1X510) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,679 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-KIR2DL4 Antibody (1X510) is a Mouse antibody targeting KIR2DL4. Anti-KIR2DL4 Antibody (1X510) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 1X510 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human KIR2DL4 / CD158D (rh KIR2DL4 / CD158D; TMPY-03652; ADY38409.1; Met1-His242). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | KIR2DL4, also known as CD158d, is a member of the killer cell Ig-like receptor (KIR) family. KIRs are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of KIR2DL4 was sensitive to inhibition by another ITIM-containing receptor. The activation-deficient mutant of KIR2DL4 inhibited the signal delivered by the activating receptor CD16. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human KIR2DL4 / CD158D Protein (TMPY-03652) |
| 抗原种属 | Human |
| 研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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