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Anti-CD59a Antibody-PE (3L156)
还可以产品编号 TMAY-03435P
Anti-CD59a Antibody-PE (3L156) 是一种 PE-conjugated Rabbit 抗体，靶向 CD59a。Anti-CD59a Antibody-PE (3L156) 可用于 FCM。
Anti-CD59a Antibody-PE (3L156)
Anti-CD59a Antibody-PE (3L156)
还可以产品编号 TMAY-03435P
Anti-CD59a Antibody-PE (3L156) 是一种 PE-conjugated Rabbit 抗体，靶向 CD59a。Anti-CD59a Antibody-PE (3L156) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CD59a Antibody-PE (3L156) is a PE-conjugated Rabbit antibody targeting CD59a. Anti-CD59a Antibody-PE (3L156) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 3L156 |
| 交叉反应 | Mouse |
| 验证活性 | Flow cytometric analysis of Mouse CD59a expression on BABL/c bone marrow erythroid cells. Cells were stained with PE-conjugated anti-Mouse CD59a. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of erythroid cells. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD59a / Protectin (rM CD59a / Protectin; TMPY-02266; NP_001104530.1; Met1-Lys95) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | Protectin, a complement regulatory protein, also known as CD59, or MIRL (membrane inhibitor of reactive lysis) is a small protein that inhibits the complement membrane attack complex by binding C5b678 and preventing C9 from binding and polymerizing. The amino-terminal 25 amino acids represented a typical signal peptide sequence and the carboxy-terminal hydrophobic amino acids were characteristic for phosphatidylinositol-anchored proteins. It was found that the CD59/Protectin antigen is a small protein sometimes associated with larger components (45 and 80 kD) in urine. CD59/Protectin antigen was released from the surface of transfected COS cells by phosphatidylinositol-specific phospholipase C, demonstrating that it is attached to the cell membrane by means of a glycolipid anchor; it is therefore likely to be absent from the surface of affected erythrocytes in the disease paroxysmal nocturnal hemoglobinuria. |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated/APC/FITC |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Mouse CD59a / Protectin Protein (TMPY-02266) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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