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顶部生物活性储存和溶解信息计算器

Anti-B7-H3 Antibody-FITC (7G630)

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产品编号 TMAY-01732F

别名 CD276 molecule, B7RP-2, B7-H3, B7H3, 4Ig-B7-H3

Anti-B7-H3 Antibody-FITC (7G630) 是一种 FITC-conjugated Mouse 抗体，靶向 B7-H3。Anti-B7-H3 Antibody-FITC (7G630) 可用于 FCM。

Anti-B7-H3 Antibody-FITC (7G630)

Anti-B7-H3 Antibody-FITC (7G630)

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Rating icon 还可以
产品编号 TMAY-01732F 别名 CD276 molecule, B7RP-2, B7-H3, B7H3, 4Ig-B7-H3

Anti-B7-H3 Antibody-FITC (7G630) 是一种 FITC-conjugated Mouse 抗体，靶向 B7-H3。Anti-B7-H3 Antibody-FITC (7G630) 可用于 FCM。

规格价格库存数量
25 T
¥ 695
5日内发货
100 T
¥ 2,195
5日内发货
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产品介绍

生物活性
产品描述
Anti-B7-H3 Antibody-FITC (7G630) is a FITC-conjugated Mouse antibody targeting B7-H3. Anti-B7-H3 Antibody-FITC (7G630) can be used in FCM.
别名CD276 molecule, B7RP-2, B7-H3, B7H3, 4Ig-B7-H3
Ig Type
Mouse IgG2b
克隆号
7G630
交叉反应
Human
特异性
Human B7-H3
验证活性
Flow cytometric analysis of anti-B7H3 (CD276) reactivity on PC-3 cells.
应用FCM
推荐剂量
10 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human B7-H3 / CD276 (rh B7-H3 / CD276; TMPY-02031; Q5ZPR3-1; Met 1-Thr 461) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to either promote or inhibit T-cell responses in various experimental systems. B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is a novel protein structurally related to the B7 family of ligands by the presence of a single set of immunoglobulin-V-like and immunoglobulin-C-like (VC) domains. Previous studies have correlated its overexpression with poor prognosis and decreased tumor-infiltrating lymphocytes in various carcinomas including uterine endometrioid carcinomas, and mounting evidence supports an immuno-inhibitory role in ovarian cancer prognosis. Recently, B7-H3 expression has been reported in several human cancers indicating an additional function of B7-H3 as a regulator of antitumor immunity.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy
偶联与修饰
偶联
FITC
其他可选修饰符
Unconjugated/APC/HRP/PE
可提供抗体种类
5
抗原信息
免疫原
Recombinant Protein: Human B7-H3 / CD276 protein (TMPY-02031)
抗原种属
Human
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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