购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-IFNAR1 Antibody (3R108)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07519

Anti-IFNAR1 Antibody (3R108) 是一种 Rabbit 抗体，靶向 IFNAR1。Anti-IFNAR1 Antibody (3R108) 可用于 WB。

Anti-IFNAR1 Antibody (3R108)

Anti-IFNAR1 Antibody (3R108)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07519

Anti-IFNAR1 Antibody (3R108) 是一种 Rabbit 抗体，靶向 IFNAR1。Anti-IFNAR1 Antibody (3R108) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,490
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
产品操作手册

产品介绍

生物活性
产品描述
Anti-IFNAR1 Antibody (3R108) is a Rabbit antibody targeting IFNAR1. Anti-IFNAR1 Antibody (3R108) can be used in WB.
Ig Type
IgG
克隆号
3R108
反应种属
Human
应用WB
推荐剂量
WB: 1:500-1000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Membrane.
组织特异性IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266S. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.02% Proclin300.
浓度1mg/ml
研究背景IFNAR1 is a member of the cytokine receptor superfamily which also includes receptors for interleukins, IFN gamma, ciliary neurotrophic factor, somatotrophin, erythropoietin, nerve growth factor, tumor necrosis factor, leukemia inhibitory factor, and oncostatin M. Some members of the family have an alpha chain with either low or high ligand binding affinity and at least one beta chain involved in signal transduction with either relatively low or no ligand binding affinity. Type I interferons, alpha and beta, induce a variety of effects on target cells including antiviral, antiproliferative, and immunomodulatory activities. The alpha and beta interferons compete to bind to a common cell surface receptor, while IFN gamma binds to a distinct receptor. IFNAR1 is very responsive to type I interferons and bind to IFN beta and IFN alpha subtypes. It is also functionally involved in signal transduction because of its association with the cytoplasmic tyrosine kinase JAK1. The type I interferons, alpha and beta, are produced by leukocytes (alpha subunits), fibroblasts (beta subtypes), lymphocytes (omega subtypes), and ruminant embryos (tau subtypes). Interferon receptors are generally found on most human cell types whatever their origin, even on cells poorly responsive to interferon. IFNAR1 is expressed on the cell surface in a variety of human cell lines.
抗原信息
免疫原
KLH conjugated synthetic peptide: human IFNAR1
抗原种属
Human
基因名称
IFNAR1
基因ID
3454
蛋白名称
Interferon alpha/beta receptor 1
Uniprot ID
P17181
功能
Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves.
化学信息
分子量Theoretical: 61 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
Related Tags: buy Anti-IFNAR1 Antibody (3R108) | purchase Anti-IFNAR1 Antibody (3R108) | Anti-IFNAR1 Antibody (3R108) cost | order Anti-IFNAR1 Antibody (3R108) | Anti-IFNAR1 Antibody (3R108) molecular weight