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Anti-SLAMF6 Antibody (4Z355)
还可以产品编号 TMAY-02159
Anti-SLAMF6 Antibody (4Z355) 是一种 Rabbit 抗体，靶向 SLAMF6。Anti-SLAMF6 Antibody (4Z355) 可用于 FCM。
Anti-SLAMF6 Antibody (4Z355)
Anti-SLAMF6 Antibody (4Z355)
还可以产品编号 TMAY-02159
Anti-SLAMF6 Antibody (4Z355) 是一种 Rabbit 抗体，靶向 SLAMF6。Anti-SLAMF6 Antibody (4Z355) 可用于 FCM。
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抗原信息
| 产品描述 | Anti-SLAMF6 Antibody (4Z355) is a Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody (4Z355) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 4Z355 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human SLAMF6(CD352) expression on human whole blood lymphocytes. Cells were stained with purified anti-Human SLAMF6(CD352), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| 应用 | FCM |
| 推荐剂量 | FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Ly108/SLAMF6 (rh Ly108/SLAMF6; TMPY-01914; Q96DU3-1; Met1-Met226). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | APC/FITC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human Ly108/SLAMF6 Protein (TMPY-01914) |
| 抗原种属 | Human |
| 研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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