GITRL Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 40.9 kDa and the accession number is Q9UNG2.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 3,430 | 5日内发货 | ||
1 mg | ¥ 16,000 | 5日内发货 |
生物活性 | Testing in progress |
产品描述 | GITRL Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 40.9 kDa and the accession number is Q9UNG2. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | C-mFc |
蛋白编号 | Q9UNG2 |
别名 | TL6, GITRL, tumor necrosis factor (ligand) superfamily, member 18, AITRL, hGITRL |
蛋白构建 | The Human TNFSF18 (NP_005083.3) (Gln72-Ser199) was expressed with the Fc region of Mouse IgG2a at the C-terminus. |
蛋白纯度 | > 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC. |
分子量 | 40.9 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
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GITRL Protein, Human, Recombinant (mFc) TL6 GITRL TL 6 tumor necrosis factor (ligand) superfamily, member 18 TL-6 AITRL hGITRL recombinant recombinant-proteins proteins protein