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Anti-UMP-CMP kinase/CMPK1 Antibody (1T371) 是一种 Mouse 抗体,靶向 UMP-CMP kinase/CMPK1。Anti-UMP-CMP kinase/CMPK1 Antibody (1T371) 可用于 WB。
Anti-UMP-CMP kinase/CMPK1 Antibody (1T371) 是一种 Mouse 抗体,靶向 UMP-CMP kinase/CMPK1。Anti-UMP-CMP kinase/CMPK1 Antibody (1T371) 可用于 WB。
产品描述 | Anti-UMP-CMP kinase/CMPK1 Antibody (1T371) is a Mouse antibody targeting UMP-CMP kinase/CMPK1. Anti-UMP-CMP kinase/CMPK1 Antibody (1T371) can be used in WB. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 1T371 |
交叉反应 | Human |
验证活性 | Anti-CMPK1 mouse monoclonal antibody at 1:500 dilution. -Lane A: K562 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:22 kDa. -Observed band size:22 kDa |
应用 | WB |
推荐剂量 | WB: 1:500-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CMPK1 (rh CMPK1; TMPY-04480; P30085; Met1-Gly196). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. CMPK1 also has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. In the meanwhile, CMPK1 functions in cellular nucleic acid biosynthesis. |
偶联 | Unconjugated |
免疫原 | Recombinant Human CMPK1 Protein (TMPY-04480) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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