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Anti-CD46 Antibody (4K630)
还可以产品编号 TMAY-02293
Anti-CD46 Antibody (4K630) 是一种 Mouse 抗体，靶向 CD46。Anti-CD46 Antibody (4K630) 可用于 ELISA,IHC-P。
Anti-CD46 Antibody (4K630)
Anti-CD46 Antibody (4K630)
还可以产品编号 TMAY-02293
Anti-CD46 Antibody (4K630) 是一种 Mouse 抗体，靶向 CD46。Anti-CD46 Antibody (4K630) 可用于 ELISA,IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CD46 Antibody (4K630) is a Mouse antibody targeting CD46. Anti-CD46 Antibody (4K630) can be used in ELISA,IHC-P. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 4K630 |
| 交叉反应 | Human |
| 验证活性 | Immunochemical staining of human CD46 in human placenta with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). |
| 应用 | ELISA,IHC-P |
| 推荐剂量 | ELISA: 1:1000-1:2000; IHC-P: 1:50-1:200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD46 (rh CD46; TMPY-02023; EAW93471.1; Met 1-Asp 328). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | CD46, also known as Membrane Cofactor Protein (MCP), is a complement regulatory protein. CD46 is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 is expressed in white blood cells, platelets, epithelial cells, and fibroblasts. Human CD46 shares 5% amino acid sequence identity with mouse and rat CD46. The importance of CD46 to complement regulation is underscored by the observation that genetic loss of CD46 leads to development of atypical hemolytic-uremic syndrome (aHUS), a disease characterized by uncontrolled complement activation. CD46 is implicated in the development and/or progression of selected cancer types. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human CD46 protein (TMPY-02023) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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