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Anti-CD46 Antibody (4K630)

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Anti-CD46 Antibody (4K630)
产品编号 TMAY-02293
别名 TRA2.10, TLX, MIC10, MCP, CD46 molecule, complement regulatory protein, AHUS2

Anti-CD46 Antibody (4K630) 是一种 Mouse 抗体,靶向 CD46。Anti-CD46 Antibody (4K630) 可用于 ELISA,IHC-P。

Anti-CD46 Antibody (4K630)
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Anti-CD46 Antibody (4K630)

Rating icon 还可以
Anti-CD46 Antibody (4K630)
产品编号 TMAY-02293 别名 TRA2.10, TLX, MIC10, MCP, CD46 molecule, complement regulatory protein, AHUS2

Anti-CD46 Antibody (4K630) 是一种 Mouse 抗体,靶向 CD46。Anti-CD46 Antibody (4K630) 可用于 ELISA,IHC-P。

规格价格库存数量
100 μL
¥ 1,694
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD46 Antibody (4K630) is a Mouse antibody targeting CD46. Anti-CD46 Antibody (4K630) can be used in ELISA,IHC-P.
别名TRA2.10, TLX, MIC10, MCP, CD46 molecule, complement regulatory protein, AHUS2
Ig Type
Mouse IgG1
克隆号
4K630
交叉反应
Human
验证活性
Immunochemical staining of human CD46 in human placenta with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections).
应用
ELISA,IHC-P
推荐剂量
ELISA: 1:1000-1:2000; IHC-P: 1:50-1:200
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD46 (rh CD46; TMPY-02023; EAW93471.1; Met 1-Asp 328). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景CD46, also known as Membrane Cofactor Protein (MCP), is a complement regulatory protein. CD46 is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 is expressed in white blood cells, platelets, epithelial cells, and fibroblasts. Human CD46 shares 5% amino acid sequence identity with mouse and rat CD46. The importance of CD46 to complement regulation is underscored by the observation that genetic loss of CD46 leads to development of atypical hemolytic-uremic syndrome (aHUS), a disease characterized by uncontrolled complement activation. CD46 is implicated in the development and/or progression of selected cancer types.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human CD46 protein (TMPY-02023)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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