Name: CBB1007 trihydrochloride (1379573-92-8 free base)
Brand: TargetMol
SKU: T10699L2
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

2 mg

¥ 1,280

待询

5 mg

¥ 1,930

待询

10 mg

¥ 2,930

待询

50 mg

¥ 6,960

待询

100 mg

¥ 10,800

待询

200 mg

待询

500 mg

待询

1 mL x 10 mM (in DMSO)

¥ 2,730

待询

生物活性

产品描述	CBB1007 trihydrochloride is a selective, reversible, and substrate competitive LSD1 inhibitor (IC50: 5.27 μM for hLSD1).
体外活性	CBB1007 efficiently can block LSD1-mediated demethylation of H3K4Me2 and H3K4Me (IC50 ≤ 5 μM) with no effect on H3K4Me3 and H3K9Me2, and LSD2 and JARID1A activities. Increases H3K4Me2 and H3K4Me contents (IC50 ≤ 5 μM), and causes activation of epigenetically suppressed CHRM4/M4-ArchR and SCN3A genes in F9 cells (IC50 ≤ 3.74 μM).
别名	CBB1007 trihydrochloride

化学信息

CAS No.	2070015-03-9
密度	no data available

储存&溶解度

存储	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
溶解度信息	DMSO: 54 mg/mL, Sonication is recommended.
体内实验配方	10% DMSO+40% PEG300+5% Tween-80+45% Saline: 1.67 mg/mL, Sonication is recommeded. 请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。