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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PDZK1 Antibody (9U150)

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货号 TMAB-10158

Anti-PDZK1 Antibody (9U150) 是一种 Rabbit 抗体，靶向 PDZK1。Anti-PDZK1 Antibody (9U150) 可用于 IP,IHC-P,IHC-Fr,IF。

Anti-PDZK1 Antibody (9U150)

Anti-PDZK1 Antibody (9U150)

一键复制产品信息
Rating icon 还可以
货号 TMAB-10158

Anti-PDZK1 Antibody (9U150) 是一种 Rabbit 抗体，靶向 PDZK1。Anti-PDZK1 Antibody (9U150) 可用于 IP,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-PDZK1 Antibody (9U150) is a Rabbit antibody targeting PDZK1. Anti-PDZK1 Antibody (9U150) can be used in IP,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
9U150
反应种属
Human
应用IPIHC-PIHC-FrIF
推荐剂量
IP: 1:20-50; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Membrane. Associated with peripheral membranes. Localizes to the apical compartment of proximal tubular cells and to sinusoidal liver membranes.
组织特异性Expression is limited to epithelial cells. Expressed in the kidney (brush border of proximal tubule), pancreas, liver, and small intestine. Expressed at a lower level in the adrenal cortex, testis and stomach. Overexpressed in breast, renal and lung carcinomas.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with NHERF1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins.
抗原信息
免疫原
A synthesized peptide: human PDZK1
抗原种属
Human
基因名称
PDZK1
基因ID
5174
蛋白名称
Na(+)/H(+) exchange regulatory cofactor NHE-RF3
Uniprot ID
Q5T2W1
功能
A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function (By similarity).
化学信息
分子量Theoretical: 57 kDa. Actual: 70 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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