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Anti-CD3 epsilon Antibody (7O149) 是一种 Rabbit 抗体,靶向 CD3 epsilon。Anti-CD3 epsilon Antibody (7O149) 可用于 WB,IHC-P,IHC-Fr,IF,FCM。
Anti-CD3 epsilon Antibody (7O149) 是一种 Rabbit 抗体,靶向 CD3 epsilon。Anti-CD3 epsilon Antibody (7O149) 可用于 WB,IHC-P,IHC-Fr,IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,395 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
| 产品描述 | Anti-CD3 epsilon Antibody (7O149) is a Rabbit antibody targeting CD3 epsilon. Anti-CD3 epsilon Antibody (7O149) can be used in WB,IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | IgG |
| 克隆号 | 7O149 |
| 反应种属 | Human |
| 应用 | WBIHC-PIHC-FrIFFCM |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200; FCM: 1μg/Test |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2. |
| 免疫原 | Recombinant Protein: human CD3 epsilon |
| 抗原种属 | Human |
| 基因名称 | CD3E |
| 基因ID | |
| 蛋白名称 | T-cell surface glycoprotein CD3 epsilon chain |
| Uniprot ID | |
| 功能 | The CD3 complex mediates signal transduction. |
| 分子量 | Theoretical: 20 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |