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Anti-Adenylate kinase 2 Antibody (7E520)
还可以产品编号 TMAY-02504
Anti-Adenylate kinase 2 Antibody (7E520) 是一种 Rabbit 抗体，靶向 Adenylate kinase 2。Anti-Adenylate kinase 2 Antibody (7E520) 可用于 ICC/IF。
Anti-Adenylate kinase 2 Antibody (7E520)
Anti-Adenylate kinase 2 Antibody (7E520)
还可以产品编号 TMAY-02504
Anti-Adenylate kinase 2 Antibody (7E520) 是一种 Rabbit 抗体，靶向 Adenylate kinase 2。Anti-Adenylate kinase 2 Antibody (7E520) 可用于 ICC/IF。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Adenylate kinase 2 Antibody (7E520) is a Rabbit antibody targeting Adenylate kinase 2. Anti-Adenylate kinase 2 Antibody (7E520) can be used in ICC/IF. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 7E520 |
| 交叉反应 | Human |
| 验证活性 | Immunofluorescence staining of AK2 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-human AK2 monoclonal antibody (1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). |
| 应用 | ICC/IF |
| 推荐剂量 | ICC-IF: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human AK2 / Adenylate kinase 2 (rh AK2 / Adenylate kinase 2; P54819-1Met1-Ile239). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Adenylate kinase 2 (AK2) belongs to the Adenylate kinase family that contains three isozymes: AK1, AK2 and AK3. Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Adenylate kinase2 (AK2) is expressed in mitochondrial intermembrane space. It may play a role in apoptosis. It has been demonstrated that in apoptotic cells AK2 was translocated into the cytosol concomitantly with cytochronme C. Mutations in this gene are the cause of reticular dysgenesis. These mutations result in absent or strongly decreased protein expression. It has been also established that AK2 is specifically expressed in the stria vascularis region of the inner ear, which provides an explanation of the sensorineural deafness in these individuals. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human AK2 / Adenylate kinase 2 Protein |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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