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别名 MLN-002, MLN002, MLN-0002, LDP-02, LDP02, Entyvio
Anti-Vedolizumab Antibody (8J813) 是一种 Rabbit 抗体,靶向 Vedolizumab。Anti-Vedolizumab Antibody (8J813) 可用于 ELISA, Sandwich ELISA, Competitive ELISA。
Anti-Vedolizumab Antibody (8J813) 是一种 Rabbit 抗体,靶向 Vedolizumab。Anti-Vedolizumab Antibody (8J813) 可用于 ELISA, Sandwich ELISA, Competitive ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 40 μg | ¥ 3,218 | 5日内发货 |
| 产品描述 | Anti-Vedolizumab Antibody (8J813) is a Rabbit antibody targeting Vedolizumab. Anti-Vedolizumab Antibody (8J813) can be used in ELISA, Sandwich ELISA, Competitive ELISA. |
| 别名 | MLN-002, MLN002, MLN-0002, LDP-02, LDP02, Entyvio |
| Ig Type | IgG, κ |
| 克隆号 | 8J813 |
| 特异性 | Vedolizumab |
| 应用 | ELISASandwich ELISACompetitive ELISA |
| 推荐剂量 | ELISA: 0.01-1 µg/ml; Sandwich ELISA: 0.5-2 μg/ml; Competitive ELISA: 5-10 μg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 纯化方式 | Protein A affinity column |
| 性状 | Lyophilized. Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/mL. |
| 缓冲液 | Lyophilized with PBS, pH 7.2, containing 0.02% sodium azide. |
| 研究背景 | Vedolizumab is a humanized monoclonal antibody used primarily for the treatment of inflammatory bowel diseases (IBD), such as Crohn's disease and ulcerative colitis. The drug functions by specifically targeting the integrin α4β7, a molecule that facilitates the migration of white blood cells into the gastrointestinal (GI) tract. By blocking this interaction, Vedolizumab reduces inflammation within the GI tract, providing relief from the symptoms associated with IBD. The drug is administered intravenously and is known for its gut-selective mechanism of action, which limits systemic immune suppression and focuses treatment effects on the GI tract. It was approved by the FDA in 2014 and is marketed under the brand name Entyvio. |
| 偶联 | Unconjugated |
| 免疫原 | Vedolizumab |
| 储存方式 | The lyophilized product store at -20°C or -80°C for 12 months. The reconstituted antibody can be stored at 2°C-8°C for 2-3 weeks or at -20°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | -20°C for 1 year |