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ACE2/ACEH Protein, Human, Recombinant (His & Avi)

ACE2/ACEH Protein, Human, Recombinant (His & Avi)

产品编号 TMPK-00383
别名: ACE2, ACE-2, ACEH

ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. ACE2/ACEH Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 86.5 kDa and the accession number is Q9BYF1-1.

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ACE2/ACEH Protein, Human, Recombinant (His & Avi)
规格 价格/CNY 货期 数量
100 μg ¥ 2,660 现货
500 μg ¥ 10,600 5日内发货
1 mg ¥ 17,800 5日内发货
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产品目录号及名称: ACE2/ACEH Protein, Human, Recombinant (His & Avi) (TMPK-00383)
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生物活性
技术参数
产品性质
参考文献
生物活性 1. Immobilized Human ACE2, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for SARS-COV-2 Spike RBD, hFc Tag with the EC50 of 8.0ng/ml determined by ELISA. 2. SARS-COV-2 Spike S1, hFc Tag captured on CM5 Chip via Protein A can bind Human ACE2, His Tag with an affinity constant of 3.80 nM as determined in SPR assay.
产品描述 ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. ACE2/ACEH Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 86.5 kDa and the accession number is Q9BYF1-1.
种属 Human
表达系统 HEK293 Cells
标签 C-His-Avi
蛋白编号 Q9BYF1-1
别名 ACE2, ACE-2, ACEH
蛋白构建 Gln18-Ser740
蛋白纯度 > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量 86.5 kDa (predicted). Due to glycosylation, the protein migrates to 95-110 kDa based on Tris-Bis PAGE result.
内毒素 < 1 EU/μg by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7.

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Keywords

ACE2/ACEH Protein, Human, Recombinant (His & Avi) ACE2 ACE-2 ACE 2 ACEH recombinant recombinant-proteins proteins protein

 

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