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Anti-SNCB Antibody (7W127) 是一种 Mouse 抗体,靶向 SNCB。Anti-SNCB Antibody (7W127) 可用于 ELISA。
Anti-SNCB Antibody (7W127) 是一种 Mouse 抗体,靶向 SNCB。Anti-SNCB Antibody (7W127) 可用于 ELISA。
产品描述 | Anti-SNCB Antibody (7W127) is a Mouse antibody targeting SNCB. Anti-SNCB Antibody (7W127) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 7W127 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SNCB (Q16143; aa 1-134). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Evidence of an age-related increase of β-synuclein (SNCB) in several parts of the visual system including the retina has been reported. In general, the β-synuclein protein, codified by the SNCB gene, acts as a regulator of processes triggered by α-synuclein, and its function is altered by variations in the gene sequence, while γ-synuclein, codified by the SNCG gene, seems to play a major role in certain tumoral processes. The human alpha- and beta-synuclein genes (SNCA and SNCB) are key factors for the development of Lewy body diseases. Increased β-synuclein (Sncb) expression has been described in the aging visual system. Sncb functions as the physiological antagonist of α-synuclein (Snca), which is involved in the development of neurodegenerative diseases, such as Parkinson's and Alzheimer's diseases. |
偶联 | Unconjugated |
免疫原 | Recombinant Human SNCB Protein |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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