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顶部产品介绍化学信息储存和溶解信息计算器技术支持

PFKFB1 Protein, Human, Recombinant (His)

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货号 TMPJ-00868

别名 PFRX, PFKFB1, Fructose-2, F6PK, 6-phosphofructo-2-kinase/fructose-2, 6PF-2-K/Fru-2, 6-P2ase liver isozyme, 6-bisphosphatase 1, 6-bisphosphatase

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.

PFKFB1 Protein, Human, Recombinant (His)
其他形式的 “PFKFB1 Protein, Human, Recombinant (His)”:
FBPase1 Protein, Human, Recombinant (His, E. coli)
FBPase1 Protein, Human, Recombinant (His)

PFKFB1 Protein, Human, Recombinant (His)

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Rating icon 还可以
货号 TMPJ-00868 别名 PFRX, PFKFB1, Fructose-2, F6PK, 6-phosphofructo-2-kinase/fructose-2, 6PF-2-K/Fru-2, 6-P2ase liver isozyme, 6-bisphosphatase 1, 6-bisphosphatase

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.

规格价格库存数量
5 μg
¥ 693
6-8日内发货
10 μg
¥ 1,170
6-8日内发货
20 μg
¥ 1,860
2-4周
50 μg
¥ 3,470
2-4周
100 μg
¥ 4,930
2-4周
200 μg
¥ 7,350
2-4周
500 μg
¥ 12,100
2-4周
1 mg
¥ 18,900
2-4周
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产品介绍

生物活性
产品描述
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
种属
Human
表达系统
HEK293 Cells
标签C-6xHis
蛋白编号P16118
氨基酸序列Ser2-Tyr471
蛋白构建Ser2-Tyr471
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
缓冲液Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5% Trehalose, 1 mM EDTA, pH 7.8.
别名PFRX, PFKFB1, Fructose-2, F6PK, 6-phosphofructo-2-kinase/fructose-2, 6PF-2-K/Fru-2, 6-P2ase liver isozyme, 6-bisphosphatase 1, 6-bisphosphatase
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量60 KDa (reducing condition)
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
  • 比活力 计算器

剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

关键词

PFKFB-1PFKFB 1
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