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Anti-GPR43 Polyclonal Antibody 2
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产品编号 TMAB-00796
Anti-GPR43 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 GPR43。Anti-GPR43 Polyclonal Antibody 2 可用于 WB。
Anti-GPR43 Polyclonal Antibody 2
Anti-GPR43 Polyclonal Antibody 2
还可以产品编号 TMAB-00796
Anti-GPR43 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 GPR43。Anti-GPR43 Polyclonal Antibody 2 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-GPR43 Polyclonal Antibody 2 is a Rabbit antibody targeting GPR43. Anti-GPR43 Polyclonal Antibody 2 can be used in WB. |
| Ig Type | IgG |
| 交叉反应 | Mouse (predicted:Rat) |
| 验证活性 | Sample: Lane 1: Mouse Lung tissue lysates Lane 2: Mouse Stomach tissue lysates Primary: Anti-GPR43 (TMAB-00796) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kDa Observed band size: 52 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | G protein-coupled receptors provide attractive targets for drug therapy due to the sheer size and diversity of ligands within this receptor family. G protein-coupled receptor (GPR) GPR41 and GPR43 are related members of a homologous family of orphan G protein-coupled receptors that are tandemly encoded at a single chromosomal locus in both humans and mice. GPR43 functions as a ligand for short chain fatty acids (SCFAs), notably acetate and propionate. Bacteria in the gut produce high concentrations of SCFAs, which are subsequently released in the bloodstream, where they exert cellular effects on blood leukocytes, including calcium release, ERK1/2 activation, and inhibition of cAMP accumulation. These effects indicate a role for GPR43 in the recruitment of leukocytes, particularly polymorphonuclear cells, to sites of bacterial infection. |
| 免疫原 | KLH conjugated synthetic peptide: mouse GPR43 |
| 抗原种属 | Mouse |
| 研究领域 | GPCR |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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