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Anti-hydrogen exchanger 3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 hydrogen exchanger 3。Anti-hydrogen exchanger 3 Polyclonal Antibody 可用于 WB。
Anti-hydrogen exchanger 3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 hydrogen exchanger 3。Anti-hydrogen exchanger 3 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-hydrogen exchanger 3 Polyclonal Antibody is a Rabbit antibody targeting hydrogen exchanger 3. Anti-hydrogen exchanger 3 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Mouse,Rat (predicted:Human,Pig,Cow,Rabbit,Sheep) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane. In intestinal epithelial cells, localizes to the ileal brush border. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | NHE-3 are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics. NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption. NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly. NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells. |
| 免疫原 | KLH conjugated synthetic peptide: human NHE3 |
| 抗原种属 | Human |
| 基因名称 | SLC9A3 |
| 基因ID | |
| 蛋白名称 | Sodium/hydrogen exchanger 3 |
| Uniprot ID | |
| 功能 | Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. |
| 分子量 | Theoretical: 93 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |