购物车
- 全部删除
您的购物车当前为空
Anti-TLT-1/TREML1 Antibody (3P589)
还可以产品编号 TMAY-02153
Anti-TLT-1/TREML1 Antibody (3P589) 是一种 Mouse 抗体，靶向 TLT-1/TREML1。Anti-TLT-1/TREML1 Antibody (3P589) 可用于 ELISA(Cap)。
Anti-TLT-1/TREML1 Antibody (3P589)
Anti-TLT-1/TREML1 Antibody (3P589)
还可以产品编号 TMAY-02153
Anti-TLT-1/TREML1 Antibody (3P589) 是一种 Mouse 抗体，靶向 TLT-1/TREML1。Anti-TLT-1/TREML1 Antibody (3P589) 可用于 ELISA(Cap)。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-TLT-1/TREML1 Antibody (3P589) is a Mouse antibody targeting TLT-1/TREML1. Anti-TLT-1/TREML1 Antibody (3P589) can be used in ELISA(Cap). |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 3P589 |
| 交叉反应 | Human |
| 应用 | ELISA(Cap) |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TLT-1 / TREML1 (rh TLT-1 / TREML1; TMPY-01840; Q86YW5-1; Met1-Pro162). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Trem-like transcript 1 protein, also known as Triggering receptor expressed on myeloid cells-like protein 1, TREML1 and TLT-1, is a cytoplasm and single-pass type I membrane protein. TREML1 / TLT-1 is expressed exclusively in platelets and megakaryocytes (MKs) and that its expression is up-regulated dramatically upon platelet activation. It is a receptor that may play a role in the innate and adaptive immune response. TREML1 / TLT-1 contains the characteristic single V-set immunoglobulin (Ig) domain, its longer cytoplasmic tail is composed of both a proline-rich region and an immune receptor tyrosine-based inhibitory motif, the latter known to be used for interactions with protein tyrosine phosphatases. The triggering receptors expressed on myeloid cells (TREMs) have drawn considerable attention due to their ability to activate multiple cell types within the innate immune system, including neutrophils, monocyte / macrophages, and dendritic cells, via their association with DAP12. TREML1 / TLT-1 is prepackaged, along with CD62P, into both MK and platelet alpha-granules. Differences in thrombin-induced redistribution of CD62P and TREML1 indicate that TREML1 is not simply cargo of alpha-granules but may instead regulate granule construction or dispersal. TREML1 / TLT-1 does not function to inhibit members of the TREM family but instead may play a role in maintaining vascular hemostasis and regulating coagulation and inflammation at sites of injury. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human TLT-1 / TREML1 Protein (TMPY-01840) |
| 抗原种属 | Human |
| 研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-TLT-1/TREML1 Antibody (3P589) | purchase Anti-TLT-1/TREML1 Antibody (3P589) | Anti-TLT-1/TREML1 Antibody (3P589) cost | order Anti-TLT-1/TREML1 Antibody (3P589)
嗨！有任何问题？点我咨询
评论内容