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顶部生物活性储存和溶解信息计算器

Anti-BAK1 Antibody (2V22)

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产品编号 TMAC-00372

别名 CDN1, Bcl-2-like protein 7, Bcl2-L-7, BCL2L7, Bcl-2 homologous antagonist/killer, BAK 1, BAK, Apoptosis regulator BAK

Anti-BAK1 Antibody (2V22) 是一种 Rabbit 抗体，靶向 BAK1。Anti-BAK1 Antibody (2V22) 可用于 FCM,ICC/IF,IHC,IP,WB。

Anti-BAK1 Antibody (2V22)

Anti-BAK1 Antibody (2V22)

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Rating icon 还可以
产品编号 TMAC-00372 别名 CDN1, Bcl-2-like protein 7, Bcl2-L-7, BCL2L7, Bcl-2 homologous antagonist/killer, BAK 1, BAK, Apoptosis regulator BAK

Anti-BAK1 Antibody (2V22) 是一种 Rabbit 抗体，靶向 BAK1。Anti-BAK1 Antibody (2V22) 可用于 FCM,ICC/IF,IHC,IP,WB。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-BAK1 Antibody (2V22) is a Rabbit antibody targeting BAK1. Anti-BAK1 Antibody (2V22) can be used in FCM,ICC/IF,IHC,IP,WB.
别名CDN1, Bcl-2-like protein 7, Bcl2-L-7, BCL2L7, Bcl-2 homologous antagonist/killer, BAK 1, BAK, Apoptosis regulator BAK
Ig Type
IgG
克隆号
2V22
交叉反应
Human
验证活性
1. Western blot analysis of Bak on different lysates using anti-Bak antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: Human skeletal muscle, Lane 3: Ags.
2. Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-Bak antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-Bak antibody. Counter stained with hematoxylin.
4. ICC staining Bak in CRC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. Flow cytometric analysis of NIH/3T3 cells with Bak antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
应用FCMICC/IFIHCIPWB
推荐剂量
WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The Bcl-2 family of proteins is characterized by its ability to modulate cell death (apoptosis) under a broad range of physiologic conditions. Bcl-2 and several related proteins function to inhibit apoptosis, while other members of the Bcl-2 family, such as Bax, accelerate death under various conditions. One member of the Bcl-2 family, designated Bak, functions primarily to enhance apoptotic cell death following appropriate activating signals and counteracts the protection from apoptosis provided by Bcl-2. Expression of Bak is widespread in a broad range of cells, including various long-lived, terminally differentiated cell types, suggesting that its cell-death-inducing activity is broadly distributed and that the regulation of inhibitors of apoptosis may represent an important determinant of tissue-specific modulation of apoptosis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q16611
化学信息
分子量Theoretical: 23 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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