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Anti-BAK1 Antibody (2V22)
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产品编号 TMAC-00372
别名 CDN1, Bcl-2-like protein 7, Bcl2-L-7, BCL2L7, Bcl-2 homologous antagonist/killer, BAK 1, BAK, Apoptosis regulator BAK
Anti-BAK1 Antibody (2V22) 是一种 Rabbit 抗体，靶向 BAK1。Anti-BAK1 Antibody (2V22) 可用于 WB,ICC/IF,IHC,IP,FCM。
Anti-BAK1 Antibody (2V22)
Anti-BAK1 Antibody (2V22)
还可以产品编号 TMAC-00372 别名 CDN1, Bcl-2-like protein 7, Bcl2-L-7, BCL2L7, Bcl-2 homologous antagonist/killer, BAK 1, BAK, Apoptosis regulator BAK
Anti-BAK1 Antibody (2V22) 是一种 Rabbit 抗体，靶向 BAK1。Anti-BAK1 Antibody (2V22) 可用于 WB,ICC/IF,IHC,IP,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
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产品介绍
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抗原信息
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| 产品描述 | Anti-BAK1 Antibody (2V22) is a Rabbit antibody targeting BAK1. Anti-BAK1 Antibody (2V22) can be used in WB,ICC/IF,IHC,IP,FCM. |
| 别名 | CDN1, Bcl-2-like protein 7, Bcl2-L-7, BCL2L7, Bcl-2 homologous antagonist/killer, BAK 1, BAK, Apoptosis regulator BAK |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of Bak on different lysates using anti-Bak antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: Human skeletal muscle, Lane 3: Ags. 2. Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-Bak antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-Bak antibody. Counter stained with hematoxylin. 4. ICC staining Bak in CRC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. Flow cytometric analysis of NIH/3T3 cells with Bak antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | The Bcl-2 family of proteins is characterized by its ability to modulate cell death (apoptosis) under a broad range of physiologic conditions. Bcl-2 and several related proteins function to inhibit apoptosis, while other members of the Bcl-2 family, such as Bax, accelerate death under various conditions. One member of the Bcl-2 family, designated Bak, functions primarily to enhance apoptotic cell death following appropriate activating signals and counteracts the protection from apoptosis provided by Bcl-2. Expression of Bak is widespread in a broad range of cells, including various long-lived, terminally differentiated cell types, suggesting that its cell-death-inducing activity is broadly distributed and that the regulation of inhibitors of apoptosis may represent an important determinant of tissue-specific modulation of apoptosis. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 23 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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