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Anti-CD30/TNFRSF8 Antibody (9F649)
还可以产品编号 TMAY-01161
Anti-CD30/TNFRSF8 Antibody (9F649) 是一种 Mouse 抗体，靶向 CD30/TNFRSF8。Anti-CD30/TNFRSF8 Antibody (9F649) 可用于 FCM。
Anti-CD30/TNFRSF8 Antibody (9F649)
Anti-CD30/TNFRSF8 Antibody (9F649)
还可以产品编号 TMAY-01161
Anti-CD30/TNFRSF8 Antibody (9F649) 是一种 Mouse 抗体，靶向 CD30/TNFRSF8。Anti-CD30/TNFRSF8 Antibody (9F649) 可用于 FCM。
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偶联与修饰
抗原信息
| 产品描述 | Anti-CD30/TNFRSF8 Antibody (9F649) is a Mouse antibody targeting CD30/TNFRSF8. Anti-CD30/TNFRSF8 Antibody (9F649) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 9F649 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human TNFRSF8(CD30) expression on K562 cells. Cells were stained with purified anti-Human TNFRSF8(CD30), then a FITC-conjugated second step antibody. The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD30 / TNFRSF8 (rh CD30 / TNFRSF8; TMPY-01827; NP_001234.2; Met1-Lys379). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of lymphocytes and may also play an important role in human immunodeficiency virus replication. As a regulator of apoptosis, CD30 protein induces cell death or proliferation, depending on the cell type, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 protein expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs), and CD30 is also linked to leukocytes in patients with chronic inflammatory diseases, including lupus erythematosus, asthma, rheumatoid arthritis and atopic dermatitis (AD).Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 其他可选修饰符 | APC/FITC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human CD30 / TNFRSF8 protein (TMPY-01827) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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