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顶部生物活性储存和溶解信息计算器

Anti-CDON Antibody (8I241)

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Anti-CDON Antibody (8I241)
产品编号 TMAY-02169
别名 ORCAM, Ihog, HPE11, CDON1, CDO

Anti-CDON Antibody (8I241) 是一种 Rabbit 抗体，靶向 CDON。Anti-CDON Antibody (8I241) 可用于 ELISA。

Anti-CDON Antibody (8I241)
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Anti-CDON Antibody (8I241)

Rating icon 还可以
Anti-CDON Antibody (8I241)
产品编号 TMAY-02169 别名 ORCAM, Ihog, HPE11, CDON1, CDO

Anti-CDON Antibody (8I241) 是一种 Rabbit 抗体，靶向 CDON。Anti-CDON Antibody (8I241) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,294
5日内发货
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产品介绍

生物活性
产品描述
Anti-CDON Antibody (8I241) is a Rabbit antibody targeting CDON. Anti-CDON Antibody (8I241) can be used in ELISA.
别名ORCAM, Ihog, HPE11, CDON1, CDO
Ig Type
Rabbit IgG
克隆号
8I241
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human CDON (rh CDON; TMPY-02029; AAI14436.1; Met1-Asp963).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Cell adhesion molecule-related, down-regulated by oncogenes (CDON), also known as CDO, is an Ig superfamily member, is a component of a cell surface receptor that positively regulates skeletal myogenesis. Brother of CDO (BOC) is a cell surface receptor that derives its name from the structurally related protein, CDON. They are components of a cell surface receptor that positively regulates myogenesis in vitro. Expression of Cdo and Boc in myoblast cell lines is downregulated by the ras oncogene, and forced re-expression of either Cdo or Boc can override ras-induced inhibition of myogenic differentiation. CDO and BOC play a role in the inverse relationship between differentiation and transformation of cells in the skeletal muscle lineage. CDON binds to Bnip-2 and JLP, scaffold proteins for Cdc42 and p38alpha/beta MAPK, respectively. The Bnip-2/Cdc42 and JLP/p38alpha/beta complexes associate in a CDON-dependent manner, resulting in Bnip-2/Cdc42-dependent p38alpha/beta activation and stimulation of cell differentiation. It is proposed that CDO mediates, at least in part, the effects of cell-cell interactions between muscle precursors that are critical in myogenesis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human CDON protein (TMPY-02029)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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