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Anti-M-CSF/CSF1 Antibody (4C549)

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产品编号 TMAY-02062

Anti-M-CSF/CSF1 Antibody (4C549) 是一种 Rabbit 抗体,靶向 M-CSF/CSF1。Anti-M-CSF/CSF1 Antibody (4C549) 可用于 ELISA(Det)。

Anti-M-CSF/CSF1 Antibody (4C549)

Anti-M-CSF/CSF1 Antibody (4C549)

Rating icon 还可以
产品编号 TMAY-02062

Anti-M-CSF/CSF1 Antibody (4C549) 是一种 Rabbit 抗体,靶向 M-CSF/CSF1。Anti-M-CSF/CSF1 Antibody (4C549) 可用于 ELISA(Det)。

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产品介绍

生物活性
产品描述
Anti-M-CSF/CSF1 Antibody (4C549) is a Rabbit antibody targeting M-CSF/CSF1. Anti-M-CSF/CSF1 Antibody (4C549) can be used in ELISA(Det).
Ig Type
Monoclonal Rabbit IgG
克隆号
4C549
交叉反应
Human
应用
ELISA(Det)
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human M-CSF/CSF-1 (rh M-CSF/CSF-1; TMPY-00127; NP_757349.1; Met1-Asn190).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. M-CSF/CSF-1 is known to facilitate monocyte survival, monocyte-to-macrophage conversion, and macrophage proliferation. M-CSF/CSF-1 is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. It binds to the Colony stimulating factor 1 receptor. M-CSF/CSF-1 may also be involved in development of the placenta. The active form of M-CSF/CSF-1 is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. M-CSF/CSF-1 induces cells of the monocyte/macrophage lineage. It also plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Upregulation of M-CSF/CSF-1 in the infarcted myocardium may have an active role in healing not only through its effects on cells of monocyte/macrophage lineage, but also by regulating endothelial cell chemokine expression.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
HRP
可提供抗体种类
2
抗原信息
免疫原
Recombinant Human M-CSF/CSF-1 Protein (TMPY-00127)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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