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顶部生物活性储存和溶解信息计算器

Anti-Phospho-IRF3 (Ser386) Antibody (8Z898)

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Anti-Phospho-IRF3 (Ser386) Antibody (8Z898)
产品编号 TMAC-03230
别名 p-IRF3 (Ser386), p-IRF3 (S386), IRF3 (p-Ser386), IRF3 (p-S386)

Anti-Phospho-IRF3 (S386) Antibody (8Z898) 是一种 Rabbit 抗体，靶向 Phospho-IRF3 (S386)。Anti-Phospho-IRF3 (S386) Antibody (8Z898) 可用于 WB,ICC/IF。

Anti-Phospho-IRF3 (Ser386) Antibody (8Z898)

Anti-Phospho-IRF3 (Ser386) Antibody (8Z898)

Rating icon 还可以
Anti-Phospho-IRF3 (Ser386) Antibody (8Z898)
产品编号 TMAC-03230 别名 p-IRF3 (Ser386), p-IRF3 (S386), IRF3 (p-Ser386), IRF3 (p-S386)

Anti-Phospho-IRF3 (S386) Antibody (8Z898) 是一种 Rabbit 抗体，靶向 Phospho-IRF3 (S386)。Anti-Phospho-IRF3 (S386) Antibody (8Z898) 可用于 WB,ICC/IF。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-IRF3 (Ser386) Antibody (8Z898) 是一种 Rabbit 抗体，靶向 Phospho-IRF3 (Ser386)。Anti-Phospho-IRF3 (Ser386) Antibody (8Z898) 可用于 WB,ICC/IF。
别名p-IRF3 (Ser386), p-IRF3 (S386), IRF3 (p-Ser386), IRF3 (p-S386)
Ig Type
IgG
克隆号
8Z898
交叉反应
Human
验证活性
1. ICC staining Phospho-IRF3 (S386) in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
2. Western blot analysis of Phospho-IRF3 (S386) expression in PC-3 cell lysate.
3. Western blot analysis of Phospho-IRF3 (S386) expression in MCF7 cell lysate.
应用
WB
ICC/IF
推荐剂量
WB: 1:1000; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-α and β) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-α and interferon-β genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth; overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3γ p48 and IFN consensus sequence-binding protein (ICSBP).
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
A synthesized phosphopeptide: human IRF3 around the phosphorylation site of Ser386
抗原种属
human
Uniprot ID
Q14653
化学信息
分子量Theoretical: 47 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

pIRF3 (Ser386)pIRF3 (S386)IRF3 (pSer386)IRF3 (pS386)IRF3 (phospho-Ser386)IRF3 (phospho-S386)

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