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Anti-LYVE1 Antibody (5P861)
还可以产品编号 TMAH-00716
别名 XLKD1, LYVE-1, Lymphatic vessel endothelial hyaluronic acid receptor 1, Hyaluronic acid receptor, HAR, Extracellular link domain-containing protein 1, CRSBP-1, CRSBP1, Cell surface retention sequence-binding protein 1
Anti-LYVE1 Antibody (5P861) 是一种抗体，靶向 LYVE1。Anti-LYVE1 Antibody (5P861) 可用于 ELISA, IF, FC。
Anti-LYVE1 Antibody (5P861)
Anti-LYVE1 Antibody (5P861)
还可以产品编号 TMAH-00716 别名 XLKD1, LYVE-1, Lymphatic vessel endothelial hyaluronic acid receptor 1, Hyaluronic acid receptor, HAR, Extracellular link domain-containing protein 1, CRSBP-1, CRSBP1, Cell surface retention sequence-binding protein 1
Anti-LYVE1 Antibody (5P861) 是一种抗体，靶向 LYVE1。Anti-LYVE1 Antibody (5P861) 可用于 ELISA, IF, FC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,315 | 5日内发货 | |
| 100 μL | ¥ 2,185 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-LYVE1 Antibody (5P861) is an antibody targeting LYVE1. Anti-LYVE1 Antibody (5P861) can be used in ELISA, IF, FC. |
| 别名 | XLKD1, LYVE-1, Lymphatic vessel endothelial hyaluronic acid receptor 1, Hyaluronic acid receptor, HAR, Extracellular link domain-containing protein 1, CRSBP-1, CRSBP1, Cell surface retention sequence-binding protein 1 |
| Ig Type | Rabbit IgG |
| 克隆号 | 5P861 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunofluorescence staining of HepG2 with TMAH-00716 at 1:25, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 505-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). 2. Overlay Peak curve showing HepG2 cells surface stained with TMAH-00716 (red line) at 1:50. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1µg/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was rabbit IgG (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed. |
| 应用 | ELISA, IF, FC |
| 推荐剂量 | IF:1:50-1:200; FC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. Note=Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human LYVE1 |
| 抗原种属 | Human |
| 基因ID | 10894 |
| Uniprot ID | |
| 研究领域 | Cardiovascular |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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