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Anti-Syndecan-1 Antibody (2K646)

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产品编号 TMAY-01862

Anti-Syndecan-1 Antibody (2K646) 是一种 Rabbit 抗体,靶向 Syndecan-1。Anti-Syndecan-1 Antibody (2K646) 可用于 ELISA。

Anti-Syndecan-1 Antibody (2K646)

Anti-Syndecan-1 Antibody (2K646)

Rating icon 还可以
产品编号 TMAY-01862

Anti-Syndecan-1 Antibody (2K646) 是一种 Rabbit 抗体,靶向 Syndecan-1。Anti-Syndecan-1 Antibody (2K646) 可用于 ELISA。

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产品介绍

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产品描述
Anti-Syndecan-1 Antibody (2K646) is a Rabbit antibody targeting Syndecan-1. Anti-Syndecan-1 Antibody (2K646) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
2K646
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human Syndecan-1/CD138/SDC1 (rh Syndecan-1/CD138/SDC1; TMPY-01630; NP_002988.3; Met1-Glu251).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Syndecan-1 also known as SDC1 and CD138, is the most extensively studied member of the syndecan family. It is found mainly in epithelial cells, but its expression is developmentally regulated during embryonic development. Syndecan-1/SDC1/CD138 has been shown to mediate cell adhesion to several ECM molecules, and to act as a coreceptor for fibroblast growth factors, potent angiogenic growth factors involved also in differentiation. Syndecan-1/SDC1/CD138 expression is reduced during malignant transformation of various epithelia, and this loss correlates with the histological differentiation grade of squamous cell carcinomas, lacking from poorly differentiated tumours. In squamous cell carcinomas of the head and neck, positive syndecan-1 expression correlates with a more favourable prognosis. Experimental studies on the role of Syndecan-1 in malignant transformation have shown that Syndecan-1/SDC1/CD138 expression is associated with the maintenance of epithelial morphology, anchorage-dependent growth and inhibition of invasiveness in vitro.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human Syndecan-1/CD138/SDC1 Protein (TMPY-01630)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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