Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 11,800 | 5日内发货 | ||
500 μg | ¥ 47,500 | 5日内发货 | ||
1 mg | ¥ 79,100 | 5日内发货 |
生物活性 | Immobilized Mouse GPRC5D VLP (100μl/well) at 5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 5.7ng/ml determined by ELISA. |
产品描述 | Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA. |
种属 | Mouse |
表达系统 | HEK293 |
蛋白编号 | Q9JIL6-1 |
别名 | MGC129713, orphan G-protein coupled receptor, GPRC5D, MGC129714 |
蛋白构建 | Recombinant Mouse GPRC5D Protein-VLP is expressed from HEK293. It contains Met1-Leu344.[Accession |Q9JIL6-1] |
蛋白纯度 | ; > 95% as determined by HPLC |
分子量 | The target protein has a predicted MW of 39.90 kDa. |
内毒素 | Less than 1EU per μg by the LAL method. |
缓冲液 | Supplied as 0.22μm filtered solution in PBS (pH 7.4).Notice: If you need it for immunization, Do Not use any adjuvant. |
存储 |
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
运输方式 |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
研究背景 | Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA. |
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GPRC5D Protein-VLP, Mouse, Recombinant MGC129713 orphan G-protein coupled receptor MGC 129714 MGC-129714 MGC-129713 MGC 129713 GPRC5D MGC129714 recombinant recombinant-proteins proteins protein