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Anti-gp130/IL6ST Antibody-PE (9A213)
还可以产品编号 TMAY-01389P
Anti-gp130/IL6ST Antibody-PE (9A213) 是一种 PE-conjugated Mouse 抗体，靶向 gp130/IL6ST。Anti-gp130/IL6ST Antibody-PE (9A213) 可用于 FCM。
Anti-gp130/IL6ST Antibody-PE (9A213)
Anti-gp130/IL6ST Antibody-PE (9A213)
还可以产品编号 TMAY-01389P
Anti-gp130/IL6ST Antibody-PE (9A213) 是一种 PE-conjugated Mouse 抗体，靶向 gp130/IL6ST。Anti-gp130/IL6ST Antibody-PE (9A213) 可用于 FCM。
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抗原信息
| 产品描述 | Anti-gp130/IL6ST Antibody-PE (9A213) is a PE-conjugated Mouse antibody targeting gp130/IL6ST. Anti-gp130/IL6ST Antibody-PE (9A213) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG2a |
| 克隆号 | 9A213 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human IL6RB(CD130) expression on human whole blood Lymphocytes. Cells were stained with PE-conjugated anti-Human IL6RB(CD130). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable Lymphocytes. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL6ST/gp130/CD130 (rh IL6ST/gp130/CD130; NP_002175.2Met1-Ile618) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | Glycoprotein 130 (also known as gp130, IL6ST, IL6-beta, or CD130) is a transmembrane protein that is the founding member of the class of all cytokine receptors. CD130/gp130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and Oncostatin M (OSM). CD130/gp130 functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. CD130/gp130 plays a critical role in regulating myocyte apoptosis. Alternatively, spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1, and BSF3 can utilize gp130 for initiating signal transmission. CD130/gp130 binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. CD130/gp130 may have a role in embryonic development. The type I OSM receptor is capable of transducing OSM-specific signaling events. |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human IL6ST/gp130/CD130 Protein |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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