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Anti-TNFAIP3 Antibody (3Z618)

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Anti-TNFAIP3 Antibody (3Z618)
产品编号 TMAC-04068
别名 Zinc finger protein A20, tumor necrosis factor, alpha-induced protein 3, Tumor necrosis factor inducible protein A20, Tumor necrosis factor induced protein 3, Tumor necrosis factor alpha-induced protein 3, Tumor necrosis factor alpha induced protein 3, TNFAIP3 (A20), TNFAIP3, TNFAIP 3, TNFA1P2, TNF alpha-induced protein 3, TNAP3_HUMAN, Putative DNA-binding protein A20, Putative DNA binding protein A20, OTUD7C, OTU domain-containing protein 7C, OTU domain containing protein 7C, MGC138688, MGC138687, MGC104522, AISBL, A20

Anti-TNFAIP3 Antibody (3Z618) 是一种 Rabbit 抗体，靶向 TNFAIP3。Anti-TNFAIP3 Antibody (3Z618) 可用于 WB,ICC/IF,IHC,FCM。

Anti-TNFAIP3 Antibody (3Z618)

Anti-TNFAIP3 Antibody (3Z618)

Rating icon 还可以
Anti-TNFAIP3 Antibody (3Z618)
产品编号 TMAC-04068 别名 Zinc finger protein A20, tumor necrosis factor, alpha-induced protein 3, Tumor necrosis factor inducible protein A20, Tumor necrosis factor induced protein 3, Tumor necrosis factor alpha-induced protein 3, Tumor necrosis factor alpha induced protein 3, TNFAIP3 (A20), TNFAIP3, TNFAIP 3, TNFA1P2, TNF alpha-induced protein 3, TNAP3_HUMAN, Putative DNA-binding protein A20, Putative DNA binding protein A20, OTUD7C, OTU domain-containing protein 7C, OTU domain containing protein 7C, MGC138688, MGC138687, MGC104522, AISBL, A20

Anti-TNFAIP3 Antibody (3Z618) 是一种 Rabbit 抗体，靶向 TNFAIP3。Anti-TNFAIP3 Antibody (3Z618) 可用于 WB,ICC/IF,IHC,FCM。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-TNFAIP3 Antibody (3Z618) is a Rabbit antibody targeting TNFAIP3. Anti-TNFAIP3 Antibody (3Z618) can be used in WB,ICC/IF,IHC,FCM.
别名Zinc finger protein A20, tumor necrosis factor, alpha-induced protein 3, Tumor necrosis factor inducible protein A20, Tumor necrosis factor induced protein 3, Tumor necrosis factor alpha-induced protein 3, Tumor necrosis factor alpha induced protein 3, TNFAIP3 (A20), TNFAIP3, TNFAIP 3, TNFA1P2, TNF alpha-induced protein 3, TNAP3_HUMAN, Putative DNA-binding protein A20, Putative DNA binding protein A20, OTUD7C, OTU domain-containing protein 7C, OTU domain containing protein 7C, MGC138688, MGC138687, MGC104522, AISBL, A20
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of TNFAIP3 on Jurkat cells lysates using anti-TNFAIP3 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-TNFAIP3 antibody. Counter stained with hematoxylin.
3. ICC staining TNFAIP3 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining TNFAIP3 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining TNFAIP3 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. Flow cytometric analysis of HepG2 cells with TNFAIP3 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
WB
ICC/IF
IHC
FCM
推荐剂量
WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:100-500; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景A20 is a Cys2/Cys2 zinc finger protein that is induced by a variety of inflammatory stimuli and regulates gene expression. Specifically, A20 is induced by tumor necrosis factor (TNF) and interleukin 1 (IL-1), and acts as a negative regulator of nuclear factor κ B (NFκB) gene expression. By inhibiting NFκB activation, A20 plays a critical role in terminating NFκB responses to various stimuli. Although the C-terminal region of A20 contains seven zinc finger domains, only four of these domains are required for in vitro inhibition of TNF-induced NFκB activation. A20 also interacts with several other proteins, such as TRAF2, TRAF6 and IκB kinase (IKK) γ protein, and can thereby inhibit cell death. TXBP151, a novel A20-binding protein, may mediate the apoptotic activity of A20. Involved in the negative feedback regulation of signal transduction, A20 and A20-binding proteins may be useful as novel therapeutic tools in the treatment of a variety of diseases.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P21580
化学信息
分子量Theoretical: 90 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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